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Glutathione S-Transferase Mu 4, Human

Known as: Glutathione S-Transferase Mu 4, GST-Mu2, Glutathione S-Alkyltransferase M4 
Glutathione S-transferase Mu 4 (218 aa, ~26 kDa) is encoded by the human GSTM4 gene. This protein plays a role in the metabolism of glutathione, 1… Expand
National Institutes of Health

Related topics

Related topics

10 relations
Catabolic ProcessEnzyme GeneGSTA4 protein, humanGSTM4 gene
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Broader (1)

Glutathione S-Transferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The Redox State of Cytochrome C Modulates Resistance to Methotrexate in Human MCF7 Breast Cancer Cells
Background Methotrexate is a chemotherapeutic agent used to treat a variety of cancers. However, the occurrence of resistance… Expand
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2011
2011
Expression of glutathione-S-transferases isoenzymes and p53 in exfoliated human bladder cancer cells.
OBJECTIVES This study investigates the usefulness of glutathione-S-transferases (GST) isoenzymes and p53 immunostaining as a… Expand
Highly Cited
2009
Highly Cited
2009
GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance
Ewing's sarcoma is a malignant bone-associated tumor of children and young adults. Most cases of Ewing's sarcoma express the EWS… Expand
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Highly Cited
2007
Highly Cited
2007
Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice.
Glutathione S-transferase (Gst) enzymes are instrumental in protecting cellular macromolecules against electrophiles and products… Expand
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Highly Cited
2004
Highly Cited
2004
Identification of Mu-Class Glutathione Transferases M2-2 and M3-3 as Cytosolic Prostaglandin E Synthases in the Human Brain
Cytosolic prostaglandin (PG) E synthase was purified from human brain cortex. The N-terminal amino acid sequence, PMTLGYXNIRGL… Expand
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2001
2001
Rat glutathione S-transferase M4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathione.
Although the existence of the rat glutathione S-transferase (GST) M4 (rGSTM4) gene has been known for some time, the… Expand
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Highly Cited
1997
Highly Cited
1997
Subunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antisera.
Uncertainties about the composition and identities of glutathione S-transferases (GSTs) in human tissue have impeded studies on… Expand
Highly Cited
1993
Highly Cited
1993
Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.
The GSTM1, GSTM2, GSTM3, GSTM4, and GSTM5 glutathione transferase genes have been mapped to human chromosome 1 by using locus… Expand
1993
1993
Chromosomal mapping of the human Mu class glutathione S-transferases to 1p13.
The chromosomal localization of the human Mu class glutathione S-transferase (GST) genes has been complicated by two factors; the… Expand
1993
1993
Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4.
We have isolated the human gene and cDNA that encode the fourth member of the Mu class glutathione S-transferases (GSTs). The… Expand
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