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GSTM4 gene
Known as:
GSTM4
, Glutathione S-Transferase Mu 4 Gene
, GLUTATHIONE S-TRANSFERASE M4
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This gene plays a role in the metabolism of both glutathione and xenobiotics.
National Institutes of Health
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Related topics
Related topics
4 relations
Catabolic Process
Glutathione S-Transferase
Glutathione S-Transferase Mu 4, Human
Metabolic Detoxication, Drug
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Maresins: Specialized Proresolving Lipid Mediators and Their Potential Role in Inflammatory-Related Diseases
Shi Tang
,
Ming Wan
,
Wei Huang
,
R. Stanton
,
Yong Xu
Mediators of Inflammation
2018
Corpus ID: 4934882
Acute inflammatory responses are host-protective and normally self-limited; these responses can maintain cell homeostasis and…
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Highly Cited
2016
Highly Cited
2016
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages
Jesmond Dalli
,
Iliyan Vlasakov
,
+5 authors
C. Serhan
Proceedings of the National Academy of Sciences…
2016
Corpus ID: 11630183
Significance We recently uncovered a family of macrophage-derived molecules, coined maresin conjugates in tissue regeneration…
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2014
2014
Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.
Lalida Rojanathammanee
,
S. Rakoczy
,
H. Brown-Borg
The journals of gerontology. Series A, Biological…
2014
Corpus ID: 205082377
Ames dwarf mice are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone and live significantly longer…
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Highly Cited
2012
Highly Cited
2012
Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth.
D. Surdez
,
Magdalena Benetkiewicz
,
+11 authors
F. Tirode
Cancer Research
2012
Corpus ID: 1687499
Ewing sarcoma is a rare but aggressive disease most common in young adults. This cancer is driven by a unique chimeric fusion…
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Highly Cited
2009
Highly Cited
2009
GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance
W. Luo
,
K. Gangwal
,
S. Sankar
,
K. Boucher
,
D. Thomas
,
S. Lessnick
Oncogene
2009
Corpus ID: 5548270
Ewing's sarcoma is a malignant bone-associated tumor of children and young adults. Most cases of Ewing's sarcoma express the EWS…
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2004
2004
Promoter polymorphisms in glutathione-S-transferase genes affect transcription.
C. Guy
,
B. Hoogendoorn
,
Susan Kay Smith
,
S. Coleman
,
M. O’Donovan
,
P. Buckland
Pharmacogenetics (London)
2004
Corpus ID: 36010717
The glutathione-S-transferases are a group of enzymes that play a major role in detoxification and defence against toxic…
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2003
2003
Mu class glutathione S‐transferase mRNA isoform expression in acute lymphoblastic leukaemia
P. Kearns
,
Z. Chrzanowska-Lightowlers
,
R. Pieters
,
A. Veerman
,
A. Hall
British Journal of Haematology
2003
Corpus ID: 945754
Summary. Glutathione S‐transferases (GSTs) are implicated in cytotoxic drug resistance in leukaemia. In a previous study…
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Highly Cited
2000
Highly Cited
2000
Identification of Mu-Class Glutathione Transferases M2-2 and M3-3 as Cytosolic Prostaglandin E Synthases in the Human Brain
C. Beuckmann
,
K. Fujimori
,
Y. Urade
,
O. Hayaishi
Neurochemical Research
2000
Corpus ID: 36490150
Cytosolic prostaglandin (PG) E synthase was purified from human brain cortex. The N-terminal amino acid sequence, PMTLGYXNIRGL…
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1993
1993
Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4.
S. Zhong
,
N. Spurr
,
J. Hayes
,
C. Wolf
Biochemical Journal
1993
Corpus ID: 20721353
The Mu-Class glutathione S-transferases (GSTs) are subject to marked inter-individual variation in man, owing to the fact that 40…
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1993
1993
Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4.
K. Comstock
,
K. Johnson
,
D. Rifenbery
,
W. D. Henner
Journal of Biological Chemistry
1993
Corpus ID: 33331935
We have isolated the human gene and cDNA that encode the fourth member of the Mu class glutathione S-transferases (GSTs). The…
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