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Glutamate-Ammonia Ligase

Known as: Glutamate-Ammonia Ligase [Chemical/Ingredient], glutamate synthetase, glutamine synthase 
An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (1)

Carbon-Nitrogen Ligases

Narrower (3)

GLN2 protein, Arabidopsisglutamine synthetase 2glutamine synthetase I
GLUL geneIn BloodLGSN geneProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Efficient catalysis of ammonia borane dehydrogenation.
In the presence of an iridium pincer complex, dehydrogenation of ammonia borane (H3NBH3) occurs rapidly at room temperature in… 
Review
2006
Review
2006
Glutamine: A Trojan horse in ammonia neurotoxicity
Mechanisms involved in hepatic encephalopathy still remain to be defined. Nonetheless, it is well recognized that ammonia is a… 
Highly Cited
1992
Highly Cited
1992
High-Level Expression of a Recombinant Antibody from Myeloma Cells Using a Glutamine Synthetase Gene as an Amplifiable Selectable Marker
We report a method for introducing a glutamine synthetase (GS) selectable marker into myeloma cells in which transfectants are… 
Highly Cited
1989
Highly Cited
1989
Protein oxidation and proteolysis during aging and oxidative stress.
Review
1989
Review
1989
Conversion of amino acid residues in proteins and amino acid homopolymers to carbonyl derivatives by metal-catalyzed oxidation reactions.
Highly Cited
1988
Highly Cited
1988
N-methyl-d-aspartate promotes the survival of cerebellar granule cells in culture
Review
1987
Review
1987
Ammonia: key factor in the pathogenesis of hepatic encephalopathy.
There is substantial clinical and experimental evidence to suggest that ammonia toxicity is a major factor in the pathogenesis of… 
Highly Cited
1986
Highly Cited
1986
Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter
Highly Cited
1983
Highly Cited
1983
Identification and Differentiation of Resting Myocardial Ischemia and Infarction in Man with Positron Computed Tomography, 18F‐labeled Fluorodeoxyglucose and N‐13 Ammonia
Studies have shown that the extraction of glucose per unit flow is increased in moderately ischemic myocardium primarily due to… 
Highly Cited
1967
Highly Cited
1967
Regulation of glutamine synthetase. I. Purification and properties of glutamine synthetase from Escherichia coli.
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