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Glucocorticoid Receptor Deficiency
Known as:
Cortisol Resistance from Glucocorticoid Receptor Defect
, GCCR DEFICIENCY
, GCCR
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An autosomal dominant condition due to mutation(s) in the NR3C1 gene, encoding the glucocorticoid receptor, resulting in decreased receptor affinity…
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National Institutes of Health
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Related topics
Related topics
7 relations
Autosomal dominant inheritance
Fatigue
Hypertensive disease
Hypoglycemia
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Broader (2)
Glucocorticoid Receptor
Inborn Errors of Metabolism
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
NOTCH mutations as prognostic markers in T-ALL
Adolfo A. Ferrando
Leukemia
2010
Corpus ID: 42728802
Risk stratification plays a fundamental role in the treatment of acute lymphoblastic leukemia (ALL). Thus, patients harboring…
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Review
2003
Review
2003
A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia.
K. Renner
,
M. Ausserlechner
,
R. Kofler
Current molecular medicine
2003
Corpus ID: 42601991
Glucocorticoids (GC) control cell cycle progression and induce apoptosis in cells of the lymphoid lineage. Physiologically, these…
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Review
1997
Review
1997
Corticosteroid resistance and disease.
Roel H. DeRijk
,
Esther M. Sternberg
Annals medicus
1997
Corpus ID: 37078447
Both the unpredictability of side-effects and efficacy of glucocorticoid treatment can be problematic during clinical treatment…
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Review
1995
Review
1995
Syndromes of glucocorticoid and mineralocorticoid resistance
K. Arai
,
G. Chrousos
Steroids
1995
Corpus ID: 45225758
Highly Cited
1987
Highly Cited
1987
Interleukin 2 synthesis in the presence of steroids: a model of steroid resistance.
Kim Walker
,
Julia M. Potter
,
House Ak
Clinical and Experimental Immunology
1987
Corpus ID: 21653338
In this study interleukin 2 (IL-2) synthesis by human lymphocytes in the presence and absence of prednisolone in a group of…
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1987
1987
Decreased deoxyribonucleic acid binding of glucocorticoid-receptor complex in cultured skin fibroblasts from a patient with the glucocorticoid resistance syndrome.
H. Nawata
,
K. Sekiya
,
K. Higuchi
,
K. Kato
,
H. Ibayashi
Journal of Clinical Endocrinology and Metabolism
1987
Corpus ID: 30654963
A patient with the syndrome of glucocorticoid resistance was studied. A 27-yr-old woman initially was diagnosed as having Cushing…
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1985
1985
Lymphocyte glucocorticoid receptor binding in depressed patients with hypercortisolemia
J. Schlechte
,
B. Sherman
Psychoneuroendocrinology
1985
Corpus ID: 32653217
1984
1984
Molybdate-sensitive and molybdate-resistant activation-labile glucocorticoid-receptor mutants of the human lymphoid cell line CEM-C7.
J. Harmon
,
T. Schmidt
,
E. Thompson
Journal of Steroid Biochemistry
1984
Corpus ID: 46233006
Highly Cited
1983
Highly Cited
1983
Role of de novo DNA methylation in the glucocorticoid resistance of a T-lymphoid cell line
J. Gasson
,
T. Ryden
,
S. Bourgeois
Nature
1983
Corpus ID: 4356037
A correlation has been shown between changes in the methylation pattern of cytosine residues in DNA and the expression of…
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1982
1982
Reduced Level of Cellular Glucocorticoid Receptors in Patients with Anorexia Nervosa
K. Kontula
,
L. Andersson
,
M. Huttunen
,
R. Pelkonen
Hormone and metabolic research = Hormon- und…
1982
Corpus ID: 30535181
Specific glucocorticoid receptors were measured in circulating mononuclear leukocytes from 12 patients with anorexia nervosa and…
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