Glomerulosa Cell Adrenal Cortical Adenoma

Background. The immunohistochemical detection of aldosterone synthase (CYP11B2) and steroid 11β-hydroxylase (CYP11B1) has enabled… Expand

The mitochondrial Ca(2+) uniporter has low affinity for Ca(2+), therefore it has been assumed that submicromolar Ca(2+) signals… Expand

The mechanisms underlying the differentiation of the adrenal cortex into zones are unclear. Microarray studies on RNA from… Expand

Whereas aging has been shown to be associated with striking reductions in circulating levels of adrenal androgens in humans, the… Expand

The rat adrenal cortex is composed of three zones: the zona glomerulosa, the zona fasciculata, and the zona reticularis. Several… Expand

A novel layer of cells that do not contain both P450aldo and P45011 beta has been discovered between the zonae glomerulosa and… Expand

Adrenocorticotropin (ACTH) is known to exert an acute effect on adrenal steroidogenesis as well as long-term effects by… Expand

Recent reports have shown that RU 486, a synthetic glucocorticoid and progestin antagonist, has direct effects on tissues… Expand

Cytochrome P-450C21 was successfully demonstrated in the human adrenal glands by a peroxidase-antiperoxidase method. All three… Expand

The zonae glomerulosa and fasciculata (ZG/ZF) have been separated by microdissection from the zona reticularis (ZR) of the guinea… Expand