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Gliclazide

Known as: Gliclazida, 1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea, 1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea 
A short-acting, relatively high-potency, second-generation sulfonylurea compound with hypoglycemic activity. Gliclazide also increases peripheral… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
AIMS The impact of insulin secretagogues (ISs) on long-term major clinical outcomes in type 2 diabetes remains unclear. We… Expand
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Highly Cited
2010
Highly Cited
2010
SummaryThe action of gliclazide, a sulphonylurea with beneficial extrapancreatic effects in diabetes, may be enhanced by… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain… Expand
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Highly Cited
2008
Highly Cited
2008
The aim of the present study was to enhance the dissolution rate of gliclazide using its solid dispersions (SDs) with… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE—The purpose of this study was to investigate whether genetic variants could influence the antidiabetic efficacy of… Expand
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Highly Cited
2006
Highly Cited
2006
PurposeThe aim of this study is to define and illustrate metrics for the external evaluation of a population model.Materials and… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Progressive beta-cell failure is a characteristic feature of type 2 diabetes; consequently, beta-cell secretagogues… Expand
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Highly Cited
2004
Highly Cited
2004
Aim/hypothesisMetformin is a well-known oral hypoglycaemic agent and has been commonly used, in combination with sulphonylurea… Expand
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Highly Cited
2000
Highly Cited
2000
Diabetes is a state of increased oxidant stress and there is evidence that oxidation may play a role in the genesis of… Expand
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Review
1993
Review
1993
Gliclazide is a second generation sulphonylurea oral hypoglycaemic agent used in the treatment of non-insulin-dependent diabetes… Expand
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