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Gliclazide

Known as: Gliclazida, 1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea, 1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea 
A short-acting, relatively high-potency, second-generation sulfonylurea compound with hypoglycemic activity. Gliclazide also increases peripheral… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (5)

DiabrezideDiamicronS-1702S-852
Gliclazide:MCnc:Pt:Ser/Plas:QnIn Bloodagonistsanalogs & derivatives

Broader (1)

Hypoglycemic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Ameliorative potential of S-allylcysteine: effect on lipid profile and changes in tissue fatty acid composition in experimental diabetes.
Highly Cited
2011
Highly Cited
2011
High-performance affinity chromatography and the analysis of drug interactions with modified proteins: binding of gliclazide with glycated human serum albumin
AbstractThis study used high-performance affinity chromatography (HPAC) to examine the binding of gliclazide (i.e., a… 
2006
2006
The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial.
Highly Cited
2004
Highly Cited
2004
Detection of anti-diabetics in equine plasma and urine by liquid chromatography-tandem mass spectrometry.
2004
2004
Inhibition of ATP-sensitive K+ channels by taurine through a benzamido-binding site on sulfonylurea receptor 1.
2004
2004
Myocardial Protection from Either Ischaemic Preconditioning or Nicorandil Is Not Blocked by Gliclazide
AbstractObjective: We compared the effects of two sulphonylureas, glibenclamide and gliclazide, on ischaemic preconditioning (IPC… 
Highly Cited
1997
Highly Cited
1997
Gliclazide scavenges hydroxyl, superoxide and nitric oxide radicals: an ESR study.
The role of reactive oxygen species in diabetes and its complications are well known. Two therapeutic agents commonly used in the… 
Review
1991
Review
1991
Pathogenesis of diabetic microangiopathy: an overview.
Highly Cited
1985
Highly Cited
1985
Gliclazide Therapy Is Associated with Potentiation of Postbinding Insulin Action in Obese, Non-insulin-dependent Diabetic Subjects
Six obese, non-insulin-dependent diabetic subjects were studied before and 3 mo after treatment with the sulfonylurea gliclazide… 
1975
1975
The stimulus-secretion coupling of glucose-induced insulin release-XVII. Effects of sulfonylureas and diazoxide on insular biosynthetic activity.
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