Skip to search formSkip to main contentSkip to account menu

Genetic Predisposition to Disease

Known as: Genetic Susceptibilities, Inherited Susceptibility, Genetic Susceptibility 
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
National Institutes of Health

Related topics

Related topics

14 relations
Anticipation, GeneticAtopyGene ExpressionGene-Environment Interaction

Broader (1)

Disease susceptibility

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
GABAergic dysfunction in mood disorders
The authors review the available literature on the preclinical and clinical studies involving GABAergic neurotransmission in mood… 
Highly Cited
2001
Highly Cited
2001
A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q, and 16p.
Autism is characterized by impairments in reciprocal communication and social interaction and by repetitive and stereotyped… 
Review
2001
Review
2001
Genetic risk and behavioural change
Predictive genetic testing is currently used mainly for untreatable conditions, such as Huntington's disease, or prenatal… 
Review
1997
Review
1997
The emerging role of CTLA-4 as an immune attenuator.
Highly Cited
1996
Highly Cited
1996
Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search
Despite its high prevalence, very little is known regarding genetic predisposition to prostate cancer. A genome-wide scan… 
Highly Cited
1996
Highly Cited
1996
Two stage genome–wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
Crohn's disease (CD) and ulcerative colitis (UC), the chronic inflammatory bowel diseases (CIBD), are common causes of gastro… 
Review
1995
Review
1995
Role of bile acids in colorectal carcinogenesis.
Highly Cited
1994
Highly Cited
1994
Increase in asthma: a more toxic environment or a more susceptible population?
Serial prevalence studies have shown that childhood asthma is becoming more common. In the UK two recent studies have found that… 
Highly Cited
1988
Highly Cited
1988
Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus.
Only one third of patients with juvenile-onset insulin-dependent diabetes seem to be susceptible to diabetic nephropathy. To test… 
Highly Cited
1983
Highly Cited
1983
Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.
The families of 29 patients with systemic lupus erythematosus and 42 normal subjects were studied to determine the inheritance of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)