Genes, Lethal

Known as: Gene, Lethal, Lethal Gene, Lethal Genes 
Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES… (More)

Topic mentions per year

Topic mentions per year

1939-2018
051019392017

Papers overview

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Highly Cited
2005
Highly Cited
2005
We predicted gene function using synthetic lethal genetic interactions between null alleles in Saccharomyces cerevisiae… (More)
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Highly Cited
2000
Highly Cited
2000
A major modification to the sterile insect technique is described, in which transgenic insects homozygous for a dominant… (More)
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1993
1993
In addition to controlling somatic sexual development in Drosophila melanogaster, the Sex-lethal (Sxl) gene is required for… (More)
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Highly Cited
1990
Highly Cited
1990
Use of the sacB gene (J. L. Ried and A. Collmer, Gene 57:239-246, 1987) provides a simple, effective, positive selection for… (More)
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Highly Cited
1990
Highly Cited
1990
Somatic sexual differentiation in Drosophila melanogaster is accomplished by a hierarchy of genes of which one, Sex-lethal (Sxl… (More)
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1989
1989
We describe the construction of a new generation of vectors (pRE) for the hyperexpression of lethal gene products such as… (More)
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1987
1987
Genetic analysis of rearrangements within the multifunctional sex determining gene Sex-lethal has allowed correlation of changes… (More)
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1986
1986
In the McCune-Albright syndrome, fibrous dysplasia of bones and various forms of endocrine dysfunction are associated with… (More)
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1986
1986
Several multisystem birth defects are associated with widespread skin lesions arranged in a pattern following the lines of… (More)
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1985
1985
Genomic DNA encoding Sex-lethal, a developmental switch gene in Drosophila melanogaster that regulates sex determination and… (More)
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