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Genes, MHC Class II

Known as: MHC Class II, Class II Genes, Class II Gene 
Genetic loci in the vertebrate major histocompatibility complex that encode polymorphic products which control the immune response to specific… 
National Institutes of Health

Related topics

Related topics

20 relations
Antigen PresentationHLA Class II Histocompatibility Antigen Gamma Chain, humanHLA Class II Histocompatibility Antigen, DO Beta ChainHLA Class II Histocompatibility Antigen, DQ Alpha 1 Chain

Papers overview

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Highly Cited
2015
Highly Cited
2015
NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module
MHC class II (MHCII) genes are transactivated by the NOD-like receptor (NLR) family member CIITA, which is recruited to SXY… 
Review
2012
Review
2012
Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental…
Highly Cited
2010
Highly Cited
2010
In vivo requirement for Atg5 in antigen presentation by dendritic cells.
Highly Cited
2007
Highly Cited
2007
The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface
We have found that MHC class II (MHC II) molecules exhibit a distinctive organization on the dendritic cell (DC) plasma membrane… 
Highly Cited
2007
Highly Cited
2007
Novel regulation of MHC class II function in B cells
The presence of post‐translational regulation of MHC class II (MHC II) under physiological conditions has been demonstrated… 
Highly Cited
2006
Highly Cited
2006
B Cells Are Required for Generation of Protective Effector and Memory CD4 Cells in Response to Pneumocystis Lung Infection
B cell-deficient mice are susceptible to infection by Pneumocystis carinii f. sp. muris (PC). To determine whether this… 
Highly Cited
2001
Highly Cited
2001
MHC class II expression is regulated in dendritic cells independently of invariant chain degradation.
Highly Cited
1994
Highly Cited
1994
Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment
Targeting of MHC class II molecules to the endocytic compartment where they encounter processed antigen is determined by the… 
Highly Cited
1985
Highly Cited
1985
A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes
Class II (or Ia) antigens are highly polymorphic surface molecules which are essential for the cellular interactions involved in… 
Highly Cited
1983
Highly Cited
1983
Spontaneous H-2 mutants provide evidence that a copy mechanism analogous to gene conversion generates polymorphism in the major histocompatibility complex.
The analysis of H-2K products from spontaneously generated major histocompatibility complex (MHC) mutants and of the primary… 
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