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Generalized pustular psoriasis

Known as: Deficiency of the Interleukin-36 Receptor Antagonist, PSORIASIS 14, PUSTULAR, GPP 
An autoinflammatory disease caused by mutations in the IL36RN gene, which encodes the IL36 receptor antagonist. It is characterized by periodic… 
National Institutes of Health

Related topics

Related topics

9 relations
AcanthosisAcrodermatitis continua of HallopeauAutoimmune DiseasesAutosomal recessive inheritance

Narrower (1)

Acute generalized pustular psoriasis

Broader (1)

Psoriasis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis.
Interleukin-36 Blockade in Pustular Psoriasis Seven patients with pustular psoriasis, three with mutations in IL36RN, were… 
Highly Cited
2013
Highly Cited
2013
The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist.
Generalized pustular psoriasis (GPP) is a rare inflammatory skin disease that can be life-threatening. Recently, it has been… 
Highly Cited
2011
Highly Cited
2011
Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.
Highly Cited
2008
Highly Cited
2008
Guidelines for good pharmacoepidemiology practices (GPP)
Pharmacoepidemiologic studies provide valuable information about the health effects of healthcare products. The ISPE Guidelines… 
Highly Cited
2007
Highly Cited
2007
Multiple Scales of Temporal Variability in Ecosystem Metabolism Rates: Results from 2 Years of Continuous Monitoring in a Forested Headwater Stream
Headwater streams are key sites of nutrient and organic matter processing and retention, but little is known about temporal… 
Highly Cited
2006
Highly Cited
2006
On the use of MODIS EVI to assess gross primary productivity of North American ecosystems
[1] Carbon flux models based on light use efficiency (LUE), such as the MOD17 algorithm, have proved difficult to parameterize… 
Highly Cited
2004
Highly Cited
2004
AN EXPERIMENTAL TEST OF THE CAUSES OF FOREST GROWTH DECLINE WITH STAND AGE
The decline in aboveground wood production after canopy closure in even-aged forest stands is a common pattern in forests, but… 
Highly Cited
2001
Highly Cited
2001
Carbon in catchments: connecting terrestrial carbon losses with aquatic metabolism
For a majority of aquatic ecosystems, respiration ( R ) exceeds autochthonous gross primary production (GPP). These systems have… 
Highly Cited
1992
Highly Cited
1992
The role of streptococcal infection in the initiation of guttate psoriasis.
BACKGROUND AND DESIGN Although the association between streptococcal infection and guttate psoriasis is well known, to date there… 
Highly Cited
1990
Highly Cited
1990
Validation of Sickness Impact Profile and Psoriasis Disability Index in psoriasis
A prospective cross‐sectional questionnaire study of 32 patients with psoriasis was carried out in order to validate the use of… 
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