Skip to search formSkip to main contentSkip to account menu

Gene Silencing

Known as: Silencing, Gene, Gene Inactivation, silencing gene 
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA… 
National Institutes of Health

Related topics

Related topics

4 relations
DNA Methylationaspects of radiation effectsphysiological aspectsregulation of gene silencing

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
siRNA delivery by a transferrin‐associated lipid‐based vector: a non‐viral strategy to mediate gene silencing
RNA interference provides a powerful technology for specific gene silencing. Therapeutic applications of small interfering RNA… 
Highly Cited
2006
Highly Cited
2006
DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner.
DNA methylation is a major epigenetic mechanism that has been suggested to control developmental gene regulation during… 
Highly Cited
2006
Highly Cited
2006
Rapid induction of transcriptional and post-transcriptional gene silencing using a novel Cucumber mosaic virus vector
We developed a novel RNA virus vector based on the Cucumber mosaic virus (CMV), which is able to efficiently induce gene… 
Highly Cited
2006
Highly Cited
2006
Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-beta1 promoter for treatment of progressive renal diseases.
Pyrrole-imidazole (Py-Im) polyamides are nuclease-resistant novel compounds that inhibit gene expression by binding to the minor… 
Highly Cited
2005
Highly Cited
2005
The Corfu δβ thalassemia deletion disrupts γ-globin gene silencing and reveals post-transcriptional regulation of HbF expression Running title: Corfu δβ thalassemia and β-globin regulation
The 7.2 kilobase (kb) Corfu δβ thalassemia mutation is the smallest known deletion encompassing a region upstream of the human… 
Review
2004
Review
2004
LNA-antisense rivals siRNA for gene silencing.
Locked nucleic acid (LNA) is a class of nucleic acid analogs possessing unprecedented binding affinity toward complementary DNA… 
Highly Cited
2002
Highly Cited
2002
Double‐stranded RNA‐mediated gene silencing of cysteine proteases (falcipain‐1 and ‐2) of Plasmodium falciparum
Summary Malaria remains a public health problem of enormous magnitude, affecting over 500 million people every year. Lack of… 
Highly Cited
2002
Highly Cited
2002
Specific developmental gene silencing in the honey bee using a homeobox motif
Manipulating the expression of genes in species that are not currently used as genetic models will provide comparative insights… 
Highly Cited
2000
Highly Cited
2000
Histone H1 Is Dispensable for Methylation-Associated Gene Silencing in Ascobolus immersusand Essential for Long Life Span
ABSTRACT A gene encoding a protein that shows sequence similarity with the histone H1 family only was cloned in Ascobolus… 
Review
2000
Review
2000
Plant DNA viruses and gene silencing
Gene silencing is a multifaceted phenomenon leading to propagative down-regulation of gene expression. Gene silencing, first… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)