Gene Silencing

Known as: Silencing, Gene, Gene Inactivation, silencing gene 
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA… (More)

Topic mentions per year

Topic mentions per year

1978-2018
010020019782018

Papers overview

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Highly Cited
2008
Highly Cited
2008
The Alu elements are conserved approximately 300-nucleotide-long repeat sequences that belong to the SINE family of… (More)
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Highly Cited
2007
Highly Cited
2007
Genome-wide studies in S. cerevisiae reveal that the transcriptome includes numerous antisense RNAs as well as intergenic… (More)
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Highly Cited
2007
Highly Cited
2007
Argonautes (AGOs) are conserved proteins that contain an RNA-binding PAZ domain and an RNase H-like PIWI domain. In Arabidopsis… (More)
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Highly Cited
2006
Highly Cited
2006
In the fission yeast Schizosaccharomyces pombe, the RNA-Induced Transcriptional Silencing (RITS) complex has been proposed to… (More)
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Highly Cited
2004
Highly Cited
2004
Double-stranded RNAs (dsRNAs) induce post-transcriptional gene silencing in several species of animal and plant. In plants… (More)
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Highly Cited
2004
Highly Cited
2004
Silencing gene expression by siRNAs is rapidly becoming a powerful tool for the genetic analysis of mammalian cells. However, the… (More)
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Highly Cited
2003
Highly Cited
2003
Small interfering RNAs (siRNAs) induce sequence-specific gene silencing in mammalian cells and guide mRNA degradation in the… (More)
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Highly Cited
2001
Highly Cited
2001
In diverse organisms, small RNAs derived from cleavage of double-stranded RNA can trigger epigenetic gene silencing in the… (More)
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Highly Cited
1999
Highly Cited
1999
Posttranscriptional gene silencing (PTGS) is a nucleotide sequence-specific defense mechanism that can target both cellular and… (More)
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Highly Cited
1998
Highly Cited
1998
Many examples of extreme virus resistance and posttranscriptional gene silencing of endogenous or reporter genes have been… (More)
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