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Galactocerebrosidase, human

Known as: Galactosylceramide Beta-Galactosidase, Galactocerebroside Beta-Galactosidase, EC 3.2.1.46 
Galactocerebrosidase (685 aa, ~77 kDa) is encoded by the human GALC gene. This protein is involved in hydrolysis of galactose ester bonds of… Expand
National Institutes of Health

Papers overview

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2018
2018
PurposeNewborn screening for Krabbe disease (KD) originated in New York State in 2006 but has proven to have a high false… Expand
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2007
2007
Tandem mass spectrometry has been used for determinations of enzyme activities in biological samples. Activities in rehydrated… Expand
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Review
2005
Review
2005
Galactosylcerebroside is known to be overexpressed upon the cellular surface of a variety of cancers. In squamous cell carcinomas… Expand
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2002
2002
Globoid cell leukodystrophy (Krabbe disease) is characterized by the accumulation of a toxic metabolite, psychosine… Expand
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2001
2001
BACKGROUND Diagnosis of Niemann-Pick (A and B) and Krabbe diseases is achieved by measurement of the lysosomal enzymes acid… Expand
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2000
2000
Krabbe’s disease or globoid-cell leukodystrophy is an autosomal recessive disorder caused by a mutation of the galactocerebroside… Expand
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1998
1998
Galactocerebrosidase (GALC; EC 3.2.1.46) is a lysosomal enzyme which hydrolyzes several galactolipids and the deficiency of GALC… Expand
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1993
1993
Galactocerebrosidase (GALC, EC 3.2.1.46) was purified from human urine by a series of hydrophobic affinity column chromatography… Expand
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1986
1986
The neurological mouse mutant twitcher is characterized by a genetic deficiency of galactosylceramide beta-galactosidase… Expand
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1981
1981
Abstract A rapid and sensitive method was devised for determining β-galactosidase activity specific for galactocerebroside. A… Expand
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