GALACTOSYLCERAMIDASE

Known as: Galactocerebrosidase, D-Galactosyl-N-acylsphingosine galactohydrolase, Galactosidase, Galactosylceramide 
An enzyme that hydrolyzes galactose from ceramide monohexosides. Deficiency of this enzyme may cause globoid cell leukodystrophy (LEUKODYSTROPHY… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
01219802017

Papers overview

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2015
2015
BACKGROUND AIMS Cord blood (CB) transplantation slows neurodegeneration during certain inherited metabolic diseases. However, the… (More)
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2015
2015
BACKGROUND AIMS Cord blood (CB) transplantation slows neurodegeneration during certain inherited metabolic diseases. However, the… (More)
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2008
2008
Krabbe disease, or globoid cell leukodystrophy, is an autosomal recessive disease caused by a deficiency of the lysosomal enzyme… (More)
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2005
2005
Globoid cell leukodystrophy (GLD) is a lysosomal storage disease caused by genetic deficiency of galactocerebrosidase (GALC… (More)
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1995
1995
Galactocerebrosidase (GALC) activity is deficient in all patients with globoid cell leukodystrophy (GLD). While most patients… (More)
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1994
1994
Galactocerebrosidase was purified about 22,600-fold using several hydrophobic column and gel filtration steps with a 4.8… (More)
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1993
1993
Galactocerebrosidase (GALC, EC 3.2.1.46) was purified from human urine by a series of hydrophobic affinity column chromatography… (More)
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1992
1992
Galactocerebrosidase-deficient oligodendrocytes of 'twitcher' (twi/twi) mice degenerate prematurely. Transplantation of normal… (More)
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1987
1987
Hematopoietic cell transplantation (HCT) prolongs survival in the twitcher mouse, an authentic animal model of human globoid cell… (More)
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1980
1980
Galactocerebrosidase (beta-d-galactosyl-N-acylsphingosine galactohydrolase; EC 3.2.1.46) activity of brain and liver preparations… (More)
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