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GW 7845

Known as: GW-7845, GW7845 
National Institutes of Health

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3 relations

Broader (2)

OxazolesTyrosine
analogs & derivatives

Papers overview

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2012
2012
Abstract 2580: Induction of estrogen receptor alpha by GW9662 sensitizes mammary glands to tamoxifen treatment in organ culture
Peroxisome proliferator-activated receptor gamma (PPARδ) are ligand activated nuclear receptor and binds to natural and synthetic… 
2011
2011
Stem Cell Antigen-1 Deficiency Enhances the Chemopreventive Effect of Peroxisome Proliferator–Activated Receptorγ Activation
Stem cell antigen-1 (Sca-1, Ly6A) is a glycerophosphatidylinositol (GPI)-anchored protein that was identified as a murine marker… 
2010
2010
The role of CaMKII in calcium-activated death pathways in bone marrow B cells.
Calcium is an essential signaling molecule in developing B cells, thus altering calcium dynamics represents a potential target… 
2009
2009
[Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta1-induced connective tissue growth factor expression in rat hepatic stellate cells].
OBJECTIVE To investigate the effect of peroxisome proliferator-activated receptor gamma (PPARgamma) activation on transforming… 
2009
2009
KLF 4-dependent , PPAR γ-induced expression of GPA 33 in colon cancer cell lines
The glycoprotein A33 (GPA33) is a colon cancer antigen. Phase I trials with 131I and 125I monoclonal antibody A33 in colon… 
2007
2007
An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.
Apoptosis is a critical event in the deletion of B lymphocytes prior to their migration to the periphery. Synthetic peroxisome… 
2006
2006
Activation of multiple mitogen-activated protein kinases in pro/pre-B cells by GW7845, a peroxisome proliferator-activated receptor gamma agonist, and their contribution to GW7845-induced apoptosis.
There is growing interest in using peroxisome proliferator-activated receptor (PPAR) gamma agonists as chemotherapeutic agents in… 
Highly Cited
2005
Highly Cited
2005
Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis.
Peroxisome proliferator-activated receptor (PPAR) represents a ligand-dependent nuclear receptor family that regulates multiple… 
2002
2002
15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma.
1999
1999
Carcinogenesis ) , GW 7845 , Inhibits Rat Mammary γ ( PPAR-γ Receptor-A New Ligand for the Peroxisome Proliferator-Activated Updated
We have tested a new ligand for peroxisome proliferator-activated receptor-g, GW7845, as an inhibitor of experimental mammary… 
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