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GV 150526A

Known as: GV-150526A, GV150526, GV150526A 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
PurposeThe aim of this study was to investigate and quantify drug movement to the brain via the neuro-olfactory system after… Expand
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Highly Cited
2006
Highly Cited
2006
Background and Purpose: Gavestinel, GV150526, is a selective antagonist at the glycine site of the N-methyl-D-aspartate receptor… Expand
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Highly Cited
2002
Highly Cited
2002
SUMMARY During cerebral ischaemia, glutamate is released in supraphysiological amounts and is toxic to brain tissue. This… Expand
Highly Cited
2001
Highly Cited
2001
CONTEXT Elucidation of the ischemic cascade has helped stimulate development of neuroprotective drugs aimed at limiting brain… Expand
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Highly Cited
2001
Highly Cited
2001
GV150526 is a novel glycine antagonist at the NMDA receptor complex. It is a potent neuroprotective agent in animal models of… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND PURPOSE GV150526 is a novel glycine site antagonist at the N-methyl-D-aspartate receptor complex. It is a potent… Expand
1999
1999
The utility of interspecies scaling in early drug development has been extensively debated. The authors discuss the dose… Expand
1999
1999
A series of analogues of the indole-2-carboxylate GV150526, currently in clinical trials as a potential neuroprotective agent for… Expand
Highly Cited
1997
Highly Cited
1997
The neuroprotective activity of the novel, selective glycine antagonist GV150526 was assessed in the middle artery occlusion… Expand
1997
1997
The N-methyl-D-aspartate (NMDA) receptor is a ligand-gated ion channel which is widely distributed in the central nervous system… Expand