Preparation and physicochemical characterization of acyclovir cocrystals with improved dissolution properties.
- G. Bruni, Mariarosa Maietta, A. Marini
- Materials ScienceJournal of Pharmacy and Science
- 1 November 2013
Two cocrystals of this drug were successfully produced with glutaric acid and fumaric acid as conformers, using a cogrinding method, and the IDR of the new phases were much faster compared with acyclovir, particularly at neutral pH.
Drug-excipient compatibility studies by physico-chemical techniques; The case of Atenolol
We apply a range of techniques (thermal methods, microscopy, X-ray diffraction, IR spectroscopy) to characterize a drug (atenolol), several excipients (PVP=polyvinylpyrrolidone, MGST=magnesium…
Drug-excipient compatibility studies by physico-chemical techniques; The case of Indomethacin
This work exemplifies a general method of studying the drug excipient interactions, with the aim of predicting rapidly and inexpensively the long term stability of their mixtures. We study the…
Drug-Excipient Compatibility Studies. Search of interaction indicators
It is shown that simultaneous thermal analysis is the best suited technique in the search of interaction indicators, with respect to the role of the water vapour, which has been found to be a critical parameter for all systems.
Kinetic Parameters from Thermogravimetric Data
Abstract The "differential" method of Achar, Brindley and Sharp (ABS) and the "integral" one of Coats and Redfern (CR) are applied to the dehydration of BaBr2-H20 and HCOOLi-H20 and to the thermal…
Determination of the nateglinide polymorphic purity through DSC.
Physico-chemical characterisation of different solid forms of spironolactone
Thermodynamic relationships between nateglinide polymorphs.
Effect of mechanical activation on the preparation of SrTiO3 and Sr2TiO4 ceramics from the solid state system SrCO3–TiO2
Nature of conductivity in SrSiO3-based fast ion conductors.
- C. Tealdi, L. Malavasi, I. Uda, C. Ferrara, V. Berbenni, P. Mustarelli
- Materials ScienceChemical Communications
- 30 October 2014
It is shown that Na-doping unlikely takes place in the silicate phase, and that a secondary glassy phase is at the origin of the transport properties, thereby suggesting that the conductivity is due only to a limited extent to oxide ion migration in the crystalline system.