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GUCY2C gene

Known as: GUC2C, heat stable enterotoxin receptor, STAR 
This gene is involved in ligand-dependent cGMP synthase activity.
National Institutes of Health

Papers overview

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2016
2016
Obesity is a well-known risk factor for colorectal cancer but precisely how it influences risks of malignancy remains unclear… Expand
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2016
2016
OBJECTIVE Congenital sodium diarrhoea (CSD) refers to a form of secretory diarrhoea with intrauterine onset and high faecal… Expand
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2016
2016
Enterotoxigenic Escherichia coli (ETEC) causes ∼20% of the acute infectious diarrhea (AID) episodes worldwide, often by producing… Expand
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2014
2014
BACKGROUND Although colorectal cancer is a disease characterized by sequential accumulation of mutations in epithelial cells… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Familial diarrhea disorders are, in most cases, severe and caused by recessive mutations. We describe the cause of a… Expand
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2012
2012
The barrier separating mucosal and systemic compartments comprises epithelial cells, annealed by tight junctions, limiting… Expand
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2012
2012
Meconium ileus, intestinal obstruction in the newborn, is caused in most cases by CFTR mutations modulated by yet-unidentified… Expand
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Highly Cited
2011
Highly Cited
2011
Intestinal enteroendocrine cells are critical to central regulation of caloric consumption, since they activate hypothalamic… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS GUCY2C is the intestinal receptor for the paracrine hormones guanylin and uroguanylin that converts guanosine-5… Expand
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Highly Cited
2009
Highly Cited
2009
CONTEXT The established relationship between lymph node metastasis and prognosis in colorectal cancer suggests that recurrence in… Expand
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