GSTM1 gene

Known as: GLUTATHIONE TRANSFERASE, CLASS MU, 1, MU, GLUTATHIONE S-TRANSFERASE M1 
This gene plays a role in the phase II metabolism of both endogenous compounds and xenobiotics.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
In many cases, silencing of gene expression by CpG methylation is causally involved in carcinogenesis. Furthermore, cancer… (More)
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Highly Cited
2005
Highly Cited
2005
The glutathione S-transferase (GST) gene superfamily encodes for enzymes involved in conjugation of electrophilic compounds to… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES Asthma is a complex multifactorial disease with an obvious genetic predisposition, immunological aberration, and… (More)
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Highly Cited
1998
Highly Cited
1998
Genetically based differences in carcinogen metabolism have been related to polymorphisms of the cytochrome P450IA1 gene (CYPIA1… (More)
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Highly Cited
1998
Highly Cited
1998
A partial physical map has been constructed of the human class Mu glutathione S-transferase genes on chromosome 1p13.3. The… (More)
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Review
1997
Review
1997
The mu (GSTM1 and theta (GSTT1) members of the glutathione S-transferase multigene family are candidate cancer susceptibility… (More)
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Highly Cited
1996
Highly Cited
1996
A deletion polymorphism in glutathione S-transferase theta (GSTT1) gene was recently discovered in humans. Similar to the GSTM1… (More)
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Highly Cited
1996
Highly Cited
1996
Allelism in glutathione S-transferase GSTM1 and GSTT1 has been suggested as a risk factor in various cancers. Accordingly, we… (More)
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Highly Cited
1996
Highly Cited
1996
Genes coding for the glutathione S-transferase M1 (GSTM1) and Theta 1 (GSTT1) proteins are polymorphic in humans and these genes… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Numerous studies have associated bladder cancer with exposure to carcinogens present in tobacco smoke and other… (More)
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