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GSTM1 gene

Known as: GLUTATHIONE TRANSFERASE, CLASS MU, 1, MU, GLUTATHIONE S-TRANSFERASE M1 
This gene plays a role in the phase II metabolism of both endogenous compounds and xenobiotics.
National Institutes of Health

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Related topics

4 relations
Carcinoma of lungGSTM1 protein, humanMetabolic Detoxication, Drug

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GSTM1 wt Allele

Papers overview

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Highly Cited
2010
Highly Cited
2010
Animal model of autism using GSTM1 knockout mice and early post-natal sodium valproate treatment
Review
2009
Review
2009
The Prostate 69 : 662 ^ 688 ( 2009 ) AnUpdatingMeta-Analysis of the GSTM 1 , GSTT 1 , and GSTP 1 Polymorphisms andProstateCancer : AHuGEReview
It has been postulated that individuals with GSTM1, GSTT1 deficiency and, GSTP1 (105Ile/Val transition) have increased… 
Review
2008
Review
2008
CYP1A1 and GSTM1 polymorphisms and lung cancer risk in Chinese populations: a meta-analysis.
Highly Cited
2005
Highly Cited
2005
Polymorphisms of drug‐metabolizing enzymes and risk of childhood acute lymphoblastic leukemia
The involvement of phase I and II enzymes is well documented in the metabolism of a wide range of drugs and xenobiotics. Single… 
Highly Cited
2004
Highly Cited
2004
Genetic Polymorphisms in GSTM1, GSTP1, and GSTT1 and the Risk for Breast Cancer
Purpose: We studied the relation of breast cancer to common deletion mutations in GSTM1 and GSTT1 and the functional Ile105Val… 
Highly Cited
2003
Highly Cited
2003
Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia
The role of methylenetetrahydrofolate reductase (MTHFR C677T), glutathione S‐transferases (GSTM1 and GSTT1 null, GSTP1 Ile105Val… 
Highly Cited
2001
Highly Cited
2001
Effect of glutathione S-transferase M1 genotype on progression of atherosclerosis in lifelong male smokers.
Highly Cited
2000
Highly Cited
2000
Polymorphisms of N-acetyltransferase 2, glutathione S-transferase mu and theta genes as risk factors of bladder cancer in relation to asthma and tuberculosis.
Review
1999
Review
1999
Glutathione S-transferase M1 status and lung cancer risk: a meta-analysis.
Interindividual differences in lung cancer susceptibility may be mediated in part through polymorphic variability in the… 
Highly Cited
1984
Highly Cited
1984
The human glutathione S‐transferases: studies on the tissue distribution and genetic variation of the GST1, GST2 and GST3 isozymes
1. Three sets of isozymes of glutathione‐S‐transferase (GST) have been identified in human tissues. They differ in their tissue… 
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