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Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer.
microRNAs (miRNAs) have been reported to play a crucial role in regulating a variety of genes pivotal for tumor metastasis. miR-126 is well known as one of the angiogenesis regulatory miRNAs. RecentExpand
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Osteoblast–osteoclast interactions
ABSTRACT Bone homeostasis depends on the resorption of bones by osteoclasts and formation of bones by the osteoblasts. Imbalance of this tightly coupled process can cause diseases such asExpand
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miR-182 promotes cell growth and invasion by targeting forkhead box F2 transcription factor in colorectal cancer.
Forkhead box F2 transcription factor (FoxF2) has been described to promote organ development, extracellular matrix (ECM) synthesis and epithelial-mesenchymal interaction. Although recent studiesExpand
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Combined p53‐related genetic variants together with HPV infection increase oral cancer risk
To explore the role of polymorphisms of p53‐related genes in etiology of oral cancer, we investigated joint effects of seven putatively functional polymorphisms of p53 (codon 72 Arg/Pro), p73 (4/14Expand
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Detection of cell‐free BIRC5 mRNA in effusions and its potential diagnostic value for differentiating malignant and benign effusions
The detection of circulating nucleic acids has long been explored for the diagnosis of a variety of clinical conditions. The aim of this study was to detect the cell‐free mRNA expression of BIRC5 inExpand
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Effects of lead and cadmium co-exposure on bone mineral density in a Chinese population.
It has been indicated that both cadmium (Cd) and lead (Pb) may have adverse effects on the bone. However, most studies have only focused on a single factor. The primary and main and interactiveExpand
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Identification of Clostridium difficile ribotype 027 for the first time in Mainland China.
was 1.60 (95% confidence interval [CI], 1.02-2.51), P = .04. 2. Of those subjects who received a PPI and vancomycin alone, the relapse rate was 28.0% (7/25), compared to 10.3% (8/78) in those whoExpand
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Variants in nucleotide excision repair core genes and susceptibility to recurrence of squamous cell carcinoma of the oropharynx
Genetically determined capacity for NER may modulate both cancer risk and prognosis. Thus, we evaluated associations of seven selected variants in the NER core genes with recurrence risk in 658Expand
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Differentiation of clear cell and non-clear cell renal cell carcinomas by all-relevant radiomics features from multiphase CT: a VHL mutation perspective
ObjectivesTo develop a radiomics model with all-relevant imaging features from multiphasic computed tomography (CT) for differentiating clear cell renal cell carcinoma (ccRCC) from non-ccRCC and toExpand
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Validation of methylation-sensitive high-resolution melting (MS-HRM) for the detection of stool DNA methylation in colorectal neoplasms.
BACKGROUND Methylation-sensitive high-resolution melting (MS-HRM) is a new technique for assaying DNA methylation, but its feasibility for assaying stool in patients with colorectal cancer (CRC) isExpand
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