GSK343
National Institutes of Health
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The TMPRSS2-ERG gene fusion occurs frequently in prostate cancers and leads to over-expression of the ETS transcription factor…
Enhancer of zeste homolog 2 (EZH2) has been emerged as novel anticancer target. Various EZH2 small-molecule inhibitors have been…
A major question facing the use of epigenetic therapies in cancer is specificity in modulating gene expression. In addition…
INTRODUCTION: Ependymoma is the second most common malignant paediatric tumour of the central nervous system, accounting for 6-12…