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GSK2830371

National Institutes of Health

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2 relations

Broader (2)

AminopyridinesDipeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Wild-type p53-induced phosphatase 1 promotes vascular smooth muscle cell proliferation and neointima hyperplasia after vascular injury via p-adenosine 5′-monophosphate-activated protein kinase…
Objectives: Vascular smooth muscle cell (VSMC) proliferation is a crucial cause of vascular neointima hyperplasia and restenosis… 
2017
2017
Abstract 2151: Inhibition of WIP1/PPM1D phosphatase by GSK2830371 potentiates the growth inhibitory and cytotoxic activity of MDM2 antagonists (nutlin-3, RG7388 and HDM201) in cutaneous melanoma…
Cutaneous melanoma is the most serious skin malignancy. The current study aimed to investigate the WIP1 inhibitor GSK2830371 and… 
2016
2016
Abstract 3730: The PPM1D inhibitor GSK2830371 has p53-dependent anti-lymphoma effects and enhances bortezomib-induced apoptosis in mantle cell lymphoma
p53 mutations are relatively rare (∼15%) in mantle cell lymphoma (MCL). Chemotherapeutic agents induce DNA damage, p53… 
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