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GRIN2A protein, human

Known as: N-Methyl-D-Aspartate Receptor Subunit 2A, NMDAR2A, Glutamate [NMDA] Receptor Subunit Epsilon-1 
Glutamate receptor ionotropic, NMDA 2A (1464 aa, ~165 kDa) is encoded by the human GRIN2A gene. This protein is involved in the modulation of ion… 
National Institutes of Health

Related topics

Related topics

19 relations
Alzheimer's Disease Pathway KEGGCellular MembraneGRIN2A geneGRIN2A wt Allele

Broader (1)

N-methyl D-aspartate receptor subtype 2A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Calpain-Mediated Signaling Mechanisms in Neuronal Injury and Neurodegeneration
Calpain is a ubiquitous calcium-sensitive protease that is essential for normal physiologic neuronal function. However… 
Highly Cited
2007
Highly Cited
2007
Molecular Pain BioMed Central
  • 2007
  • Corpus ID: 5654370
Review
2006
Review
2006
NMDA receptor function: subunit composition versus spatial distribution
NMDA receptors (NMDARs) play a pivotal role in the regulation of neuronal communication and synaptic function in the central… 
Highly Cited
2006
Highly Cited
2006
Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome
Highly Cited
2005
Highly Cited
2005
NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
Injury to oligodendrocyte processes, the structures responsible for myelination, is implicated in many forms of brain disorder… 
Highly Cited
1999
Highly Cited
1999
PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.
Fyn, a member of the Src-family protein-tyrosine kinase (PTK), is implicated in learning and memory that involves N-methyl-D… 
Highly Cited
1996
Highly Cited
1996
Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics
NMDA receptor antagonists can induce a schizophrenia-like psychosis, but the role of NMDA receptors in the pathophysiology of… 
Highly Cited
1995
Highly Cited
1995
NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum
N-Methyl-D-aspartate (NMDA) receptors are enriched in the neostriatum and are thought to mediate several actions of glutamate… 
Highly Cited
1994
Highly Cited
1994
The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
Neuronal plasticity associated with learning, memory and development is controlled, in part, by NMDA receptors, which are… 
Highly Cited
1994
Highly Cited
1994
The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition
The relationship between four pharmacologically distinct NMDA receptor subtypes, identified in radioligand binding studies, and… 
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