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GREB1 gene

Known as: growth regulation by estrogen in breast cancer 1, Growth Regulation By Estrogen In Breast Cancer 1 Gene, GREB1 PROTEIN 
This gene may be involved in hormone-dependent cell proliferation.
National Institutes of Health

Related topics

Related topics

2 relations
Cancer Cell Growth RegulationProtein GREB1

Papers overview

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Highly Cited
2014
Highly Cited
2014
TRIM28 regulates RNA polymerase II promoter proximal pausing and pause release
Promoter-proximal pausing of RNA polymerase II (Pol II) is a major checkpoint in transcription. An unbiased search for new human… Expand
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Highly Cited
2013
Highly Cited
2013
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.
Estrogen receptor-α (ER) is the driving transcription factor in most breast cancers, and its associated proteins can influence… Expand
Highly Cited
2013
Highly Cited
2013
Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
IntroductionEstrogen signaling is pivotal in the progression of estrogen receptor positive breast cancer primarily by the… Expand
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Highly Cited
2012
Highly Cited
2012
Genome-wide association meta-analysis identifies new endometriosis risk loci
We conducted a genome-wide association meta-analysis of 4,604 endometriosis cases and 9,393 controls of Japanese and European… Expand
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Highly Cited
2012
Highly Cited
2012
The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal endometriosis.
OBJECTIVE To analyze the expression of estrogen receptors α and β as well as their target genes implicated in proliferation, c… Expand
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Highly Cited
2012
Highly Cited
2012
Development of transcriptomic biomarker signature in human saliva to detect lung cancer
Lung cancer is the leading cause of cancer death for both men and women worldwide. Since most of the symptoms found for lung… Expand
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Highly Cited
2007
Highly Cited
2007
Regulation of GREB1 Transcription by Estrogen Receptor α through a Multipartite Enhancer Spread Over 20 kb of Upstream Flanking Sequences*
Estrogen receptors activate transcription in part through direct interactions with specific DNA motifs, called estrogen response… Expand
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Highly Cited
2006
Highly Cited
2006
GREB1 is a novel androgen‐regulated gene required for prostate cancer growth
Gene regulated in breast cancer 1 (GREB1) is a novel estrogen‐regulated gene shown to play a pivotal role in hormone‐stimulated… Expand
Highly Cited
2005
Highly Cited
2005
GREB1 is a critical regulator of hormone dependent breast cancer growth
SummaryBackground Estrogen plays a central role in breast cancer pathogenesis and many potent risk factors for the development of… Expand
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Highly Cited
2000
Highly Cited
2000
PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer.
The function of estrogen in breast cancer proliferation and progression is likely to be due to the expression of a repertoire of… Expand
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