• Publications
  • Influence
Flavonoids, Breast Cancer Chemopreventive and/or Chemotherapeutic Agents.
TLDR
Empirical studies suggest that an enrich flavonoids diet is linked to a decreased risk of breast cancer, due to the alteration of numerous signalling pathways involved in cancer-related phenomena such as inflammation and proliferation. Expand
Phytotherapy and women's reproductive health: the Cameroonian perspective.
TLDR
The African pharmacopoeia thus provides plants used for preventing and/or treating gynecological infections, dysmenorrhea, irregular menstruations, oligomenorrhea or protracted menstruation, and infertility, and plants used as antimicrobians, emmenagogues, or as suppressors of uterine flow. Expand
Effects of Millettia macrophylla (Fabaceae) extracts on estrogen target organs of female wistar rat.
TLDR
Results indicate that M. macrophylla extracts have estrogen-like effects supporting their traditional use in Cameroon to alleviate some menopausal problems. Expand
Preventive Effects of an Extract of Erythrina Lysistemon (Fabaceae) on Some Menopausal Problems: Studies on the Rat
TLDR
It is suggested that oral administration of 200mg/kg/d of EL 28 days before ovariectomy prevented bone loss and EL had a transient effect on glucose intolerance, however EL significantly increased HDL-cholesterol and decreased TG levels. Expand
Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.
TLDR
The C. adansonii extract may possess antitumor constituents, which could combat breast cancer and prevent chemically-induced breast cancer in rats, and protected rats from the DNA alteration induced by DMBA and increased antioxydant enzymes activities in mammary gland tissue homogenates. Expand
Elucidation of Underlying Mechanisms by Which Millettia macrophylla Benth Induces Its Estrogenic Activity
TLDR
The results indicate that the active principles of M. macrophylla induce their beneficial effects on menopausal symptoms by activating the ERs. Expand
In vitro estrogenic activity of two major compounds from the stem bark of Erythrina lysistemon (Fabaceae).
TLDR
Results suggest that compounds 1 and 2 endow estrogenic activity and may be the active principles of Erythrina lysistemon. Expand
Effects of the extracts of some tropical medicinal plants on estrogen inducible yeast and Ishikawa screens, and on ovariectomized Wistar rats.
TLDR
The results suggest that some constituents of the extracts of Millettia conraui, Milletti drastica, Pseudarthria hookeri, Nauclea latifolia and Bridelia ferruginea may have estrogenic activity. Expand
Estrogenic effects of the ethyl-acetate extract of the stem bark of Erythrina lysistemon Hutch (Fabaceae).
TLDR
The results suggest that the extract of E. lysistemon contains secondary metabolites endowed with estrogenic activity, which is not as pronounced as those elicited in the positive control of 100 microg/kg BW/d of ethinylestradiol given orally. Expand
Timeless Is a Novel Estrogen Receptor Co-activator Involved in Multiple Signaling Pathways in MCF-7 Cells.
TLDR
This study investigated the interplay between Timeless and ERα, and showed that human Timeless is an ERα coactivator, identifying Timeless as another key regulator of ERα in controlling ERα transactivation. Expand
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