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GRB14 protein, human

Known as: GRB14, Growth Factor Receptor-Bound Protein 14, growth factor receptor-bound protein 14, human 
Member of the GRB7 family of adapter proteins; identified as a partner of the insulin receptor where it acts as a modulator of insulin signaling… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (1)

Adaptor Proteins, Signal Transducing
Adaptor Signaling Protein GeneGRB14 geneSignal TransductionSignaling Pathway Gene

Papers overview

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Highly Cited
2013
Highly Cited
2013
Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci
Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker of body fat distribution. Although… 
Review
2005
Review
2005
Grb10 and Grb14: enigmatic regulators of insulin action--and more?
The Grb proteins (growth factor receptor-bound proteins) Grb7, Grb10 and Grb14 constitute a family of structurally related… 
Highly Cited
2005
Highly Cited
2005
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14.
Highly Cited
2004
Highly Cited
2004
Improved glucose homeostasis and enhanced insulin signalling in Grb14‐deficient mice
Gene targeting was used to characterize the physiological role of growth factor receptor‐bound (Grb)14, an adapter‐type… 
Review
2004
Review
2004
Grb10: more than a simple adaptor protein.
Grb10 is a member of a superfamily of adaptor proteins that includes Grb7 and Grb14. This family of proteins shares a common… 
Highly Cited
2002
Highly Cited
2002
Identification of Novel Non-phosphorylated Ligands, Which Bind Selectively to the SH2 Domain of Grb7*
Grb7 is an adapter-type signaling protein, which is recruited via its SH2 domain to a variety of receptor tyrosine kinases (RTKs… 
Highly Cited
2002
Highly Cited
2002
Inhibition of Insulin Receptor Catalytic Activity by the Molecular Adapter Grb14*
Grb14 belongs to the Grb7 family of adapters and was recently identified as a partner of the insulin receptor (IR). Here we show… 
Highly Cited
2001
Highly Cited
2001
Identification of a Novel Human Tankyrase through Its Interaction with the Adaptor Protein Grb14*
Tankyrase is an ankyrin repeat-containing poly(ADP-ribose) polymerase originally isolated as a binding partner for the telomeric… 
Highly Cited
1998
Highly Cited
1998
Grb10 Interacts Differentially with the Insulin Receptor, Insulin-like Growth Factor I Receptor, and Epidermal Growth Factor Receptor via the Grb10 Src Homology 2 (SH2) Domain and a Second Novel…
The Grb10 protein appears to be an adapter protein of unknown function that has been implicated in insulin receptor (IR… 
Highly Cited
1996
Highly Cited
1996
Cloning and Characterization of GRB14, a Novel Member of the GRB7 Gene Family (*)
Screening of a human breast epithelial cell cDNA library with the tyrosine-phosphorylated C terminus of the epidermal growth… 
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