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GPX4 gene

Known as: PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE, PHGPx, GLUTATHIONE PEROXIDASE 4 
National Institutes of Health

Related topics

Related topics

3 relations
GLUTATHIONE PEROXIDASESMCP genephospholipid-hydroperoxide glutathione peroxidase

Papers overview

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Highly Cited
2007
Highly Cited
2007
Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer.
PURPOSE The prognosis of breast cancer varies considerably among individuals, and inherited genetic factors may help explain this… 
2006
2006
Failure of phospholipid hydroperoxide glutathione peroxidase expression in oligoasthenozoospermia and mutations in the PHGPx gene
Phospholipid hydroperoxide glutathione peroxidase (PHGPx) is a selenoprotein belonging to the family of glutathione peroxidases… 
Review
2003
Review
2003
Is there a role of glutathione peroxidases in signaling and differentiation?
Mammalian organisms contain five distinct isozymes of glutathione peroxidase (GPx), four of them being selenoproteins (for review… 
Highly Cited
2003
Highly Cited
2003
Regulation of Expression of the Phospholipid Hydroperoxide/Sperm Nucleus Glutathione Peroxidase Gene
A sperm nucleus glutathione peroxidase (snGPx), which is closely related to the phospholipid hydroperoxide glutathione peroxidase… 
2003
2003
Protective and determining factors for the overall lipid peroxidation in ultraviolet A1‐irradiated fibroblasts: in vitro and in vivo investigations
Summary  Background Lipid peroxidation (LPO) is one major effector mechanism by which ultraviolet (UV) A contributes to… 
Review
1997
Review
1997
Phospholipid hydroperoxide glutathione peroxidase (PHGPx): more than an antioxidant enzyme?
The family of glutathione peroxidases encompasses, as far, three tetrameric glutathione peroxidases (GPx) and the monomeric PHGPx… 
Highly Cited
1997
Highly Cited
1997
Expression of selenoproteins in various rat and human tissues and cell lines.
1997
1997
Cloning and sequencing of the mouse cDNA encoding a phospholipid hydroperoxide glutathione peroxidase.
Highly Cited
1991
Highly Cited
1991
Distribution of glutathione peroxidases glutathione reductase in rat brain mitochondria
1991
1991
Lethal damage to murine L1210 cells by exogenous lipid hydroperoxides: protective role of glutathione-dependent selenoperoxidases.
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