GPX1 gene

Known as: GLUTATHIONE PEROXIDASE 1, GPX1, Glutathione Peroxidase 1 Gene 
This gene plays a role in the inhibition of oxidative stress and increases cellular resistance to toxic challenges.
National Institutes of Health

Papers overview

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2011
2011
Keshan disease (KD) is an endemic cardiomyopathy associated with selenium deficiency. Recent studies indicate that glutathione… (More)
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Highly Cited
2009
Highly Cited
2009
Resveratrol, an important antioxidant found in grapes and wine, is likely to contribute to red wine's potential to prevent human… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES To investigate the activities of the main antioxidative enzymes and oxidative stress in women with depressive disorder… (More)
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Highly Cited
2009
Highly Cited
2009
Chronic reactive oxygen species (ROS) production by mitochondria may contribute to the development of insulin resistance, a… (More)
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Highly Cited
2006
Highly Cited
2006
Breast cancer may be related to oxidative stress. Breast cancer patients have been reported to have lower antioxidant enzyme… (More)
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2005
2005
Hyperhomocysteinemia contributes to vascular dysfunction and an increase in the risk of cardiovascular disease. An elevated level… (More)
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Highly Cited
2001
Highly Cited
2001
Glutathione peroxidase (GPX)-1 and gastrointestinal (GI) epithelium-specific GPX (GPX-GI), encoded by Gpx1 and Gpx2, provide most… (More)
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Highly Cited
2000
Highly Cited
2000
Oxidative stress resulting from mitochondrially derived reactive oxygen species (ROS) has been hypothesized to damage… (More)
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Highly Cited
1998
Highly Cited
1998
Glutathione peroxidases have been thought to function in cellular antioxidant defense. However, some recent studies on Gpx1… (More)
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1997
1997
Mitochondria have GPX and PHGPX activity. It has been an unsettled issue whether mitochondrial GPX is encoded by Gpx1. Unlike the… (More)
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