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GPX1 gene

Known as: GLUTATHIONE PEROXIDASE 1, GPX1, Glutathione Peroxidase 1 Gene 
This gene plays a role in the inhibition of oxidative stress and increases cellular resistance to toxic challenges.
National Institutes of Health

Related topics

Related topics

6 relations
Diabetes Mellitus, Non-Insulin-DependentGLUTATHIONE PEROXIDASEMetabolic Detoxication, DrugOxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Coculturing denuded oocytes during the in vitro maturation of bovine cumulus oocyte complexes exerts a synergistic effect on embryo development.
Highly Cited
2009
Highly Cited
2009
GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer.
Highly Cited
2008
Highly Cited
2008
Genetic variant in glutathione peroxidase 1 gene is associated with an increased risk of coronary artery disease in a Chinese population.
Highly Cited
2007
Highly Cited
2007
Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice.
To attain a profile of protein expression during diabetes, we applied proteomic analysis to glomeruli of 160-day-old db/db… 
Highly Cited
2005
Highly Cited
2005
Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy.
In many diseases, including progressive renal disorders, tissue injury and pathological intracellular signaling events are… 
Highly Cited
2005
Highly Cited
2005
Glutathione peroxidase 1 gene polymorphism and risk of recurrence in patients with superficial bladder cancer.
Highly Cited
2004
Highly Cited
2004
Genetic Variants of GPX1 and SOD2 and Breast Cancer Risk at the Ontario Site of the Breast Cancer Family Registry
There are several genes that code for enzymes, including various forms of superoxide dismutase and glutathione peroxidase, that… 
2003
2003
Overexpression of cytosolic glutathione peroxidase (GPX1) delays endothelial cell growth and increases resistance to toxic challenges.
Highly Cited
2003
Highly Cited
2003
Impacts of glutathione peroxidase-1 knockout on the protection by injected selenium against the pro-oxidant-induced liver aponecrosis and signaling in selenium-deficient mice.
1995
1995
Structure and function of the selenium translation element in the 3'-untranslated region of human cellular glutathione peroxidase mRNA.
In eukaryotes, incorporation of selenocysteine into the polypeptide chain at a UGA codon requires a unique sequence motif, or… 
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