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GPR17 protein, human

Known as: UDP/CysLT Receptor, Uracil Nucleotide/Cysteinyl Leukotriene Receptor, G-Protein Coupled Receptor 17 
Uracil nucleotide/cysteinyl leukotriene receptor (367 aa, ~41 kDa) is encoded by the human GPR17 gene. This protein plays a role in ligand-dependent… 
National Institutes of Health

Related topics

Related topics

13 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingGPR17 geneGPR17 wt Allele

Broader (1)

G-Protein-Coupled Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules*
Recent studies have recognized G protein-coupled receptors as important regulators of oligodendrocyte development. GPR17, in… 
Highly Cited
2013
Highly Cited
2013
Decoding Signaling and Function of the Orphan G Protein–Coupled Receptor GPR17 with a Small-Molecule Agonist
Activation of GPR17 prevents oligodendrocyte maturation and reveals that inhibiting GPR17 may be a therapeutic strategy to treat… 
Highly Cited
2011
Highly Cited
2011
Phenotypic Changes, Signaling Pathway, and Functional Correlates of GPR17-expressing Neural Precursor Cells during Oligodendrocyte Differentiation*
The developing and mature central nervous system contains neural precursor cells expressing the proteoglycan NG2. Some of these… 
Highly Cited
2011
Highly Cited
2011
The GPR17 receptor in NG2 expressing cells: Focus on in vivocell maturation and participation in acute trauma and chronic damage
NG2‐expressing cells comprise a population of cycling precursors that can exit the cell cycle and differentiate into mature… 
Highly Cited
2009
Highly Cited
2009
The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury.
Upon central nervous system injury, the extracellular concentrations of nucleotides and cysteinyl-leukotrienes, two unrelated… 
Highly Cited
2008
Highly Cited
2008
The Recently Identified P2Y-Like Receptor GPR17 Is a Sensor of Brain Damage and a New Target for Brain Repair
Deciphering the mechanisms regulating the generation of new neurons and new oligodendrocytes, the myelinating cells of the… 
Highly Cited
2006
Highly Cited
2006
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl‐leukotrienes receptor
Nucleotides and cysteinyl‐leukotrienes (CysLTs) are unrelated signaling molecules inducing multiple effects through separate G… 
Highly Cited
2006
Highly Cited
2006
Influence of Coulomb-attenuation on exchange-correlation functional quality.
The dependence of functional quality on the attenuation parameters--which control the limiting (r12-->0, infinity) values and the… 
Highly Cited
2005
Highly Cited
2005
New correlation factors for explicitly correlated electronic wave functions.
We have investigated the correlation factors exp(-zetar12), r12 exp(-zetar12), erfc(zetar12), and r12 erfc(zetar12) in place of… 
Highly Cited
1974
Highly Cited
1974
Round of Replication Mutant of a Drug Resistance Factor
A derivative of the R factor NR1 (called R12) has been isolated which undergoes an increased number of rounds of replication each… 
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