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GP1BA wt Allele

Known as: Platelet Glycoprotein Ib, Alpha Polypeptide Gene, BSS, CD42B 
Human GP1BA wild-type allele is located in the vicinity of 17p13.2 and is approximately 3 kb in length. This allele, which encodes platelet… 
National Institutes of Health

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17p13.2GP1BA geneGP1BA protein, humanGP1BB wt Allele

Papers overview

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Highly Cited
2008
Highly Cited
2008
Phosphoproteome of resting human platelets.
Beside their main physiological function in hemostasis, platelets are also highly involved in pathological processes, such as… 
Highly Cited
2006
Highly Cited
2006
Efficient expression of a transgene in platelets using simian immunodeficiency virus‐based vector harboring glycoprotein Ibα promoter: in vivo model for platelet‐targeting gene therapy
Platelets release several mediators that modify vascular integrity and hemostasis. In the present study, we developed a technique… 
2006
2006
Novel heterozygous missense mutation in the second leucine rich repeat of GPIbα affects GPIb/IX/V expression and results in macrothrombocytopenia in a patient initially misdiagnosed with idiopathic…
Abstract:  Recent studies have shown that heterozygous carriers of the bleeding disorder Bernard‐Soulier syndrome are… 
2003
2003
A novel missense mutation shows that GPIbbeta has a dual role in controlling the processing and stability of the platelet GPIb-IX adhesion receptor.
Glycoprotein (GP) Ibalpha is a major adhesive receptor of platelets, surface expressed as part of the GPIb-IX-V complex. However… 
2003
2003
Shielding the front-strand beta 3 of the von Willebrand factor A1 domain inhibits its binding to platelet glycoprotein Ibalpha.
Platelet adhesion to damaged vessel wall and shear-induced platelet aggregation necessitate binding of the von Willebrand factor… 
2001
2001
The CDCREL1 gene fused to MLL in de novo acute myeloid leukemia with t(11;22)(q23;q11.2) and its frequent expression in myeloid leukemia cell lines
We report on an adult patient with de novo acute myeloid leukemia (AML) with a t(11;22)(q23;q11.2) involving CDCREL1 and MLL… 
2001
2001
Glycoprotein Ib/IX/V binding to the membrane skeleton maintains shear-induced platelet aggregation.
2000
2000
Role of the Leucine-Rich Domain of Platelet GPIbα in Correct Post-translational Processing – The Nancy I Bernard-Soulier Mutation Expressed on CHO Cells
Summary The mechanisms governing the biosynthesis and surface expression of platelet adhesive receptors on parent megakaryocytes… 
Highly Cited
1999
Highly Cited
1999
The Cytoplasmic Domain of the Platelet Glycoprotein Ibα Is Phosphorylated at Serine 609*
The α chain of the platelet von Willebrand factor receptor, glycoprotein (GP) Ib, is not known to be phosphorylated. Here, we… 
Highly Cited
1998
Highly Cited
1998
Naturally occurring mutations in glycoprotein Ibalpha that result in defective ligand binding and synthesis of a truncated protein.
The platelet GPIb-V-IX complex is the receptor for the initial binding of von Willebrand factor (vWF) mediating platelet adhesion… 
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