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GP1BA wt Allele

Known as: Platelet Glycoprotein Ib, Alpha Polypeptide Gene, BSS, CD42B 
Human GP1BA wild-type allele is located in the vicinity of 17p13.2 and is approximately 3 kb in length. This allele, which encodes platelet… 
National Institutes of Health

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17p13.2GP1BA geneGP1BA protein, humanGP1BB wt Allele

Papers overview

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Highly Cited
2010
Highly Cited
2010
Relation of Platelet and Leukocyte Inflammatory Transcripts to Body Mass Index in the Framingham Heart Study
Background— Although many genetic epidemiology and biomarker studies have been conducted to examine associations of genetic… 
Highly Cited
2008
Highly Cited
2008
Phosphoproteome of resting human platelets.
Beside their main physiological function in hemostasis, platelets are also highly involved in pathological processes, such as… 
Highly Cited
2007
Highly Cited
2007
Platelet adhesion to dimeric β2‐glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibα and apolipoprotein E receptor 2′
Summary.  Background: The major antigen implicated in the antiphospholipid syndrome is beta2‐glycoprotein I (β2GPI). Dimerized… 
Review
2006
Review
2006
Bernard-Soulier syndrome (Hemorrhagiparous thrombocytic dystrophy)
Bernard-Soulier syndrome (BSS), also known as Hemorrhagiparous thrombocytic dystrophy, is a hereditary bleeding disorder… 
Highly Cited
2005
Highly Cited
2005
Effects of a new pathogen‐reduction technology (Mirasol PRT) on functional aspects of platelet concentrates
BACKGROUND: Several strategies are being developed to reduce the risk of pathogen transmission associated with platelet (PLT… 
Highly Cited
2003
Highly Cited
2003
Protein-Protein Interaction between Fli-1 and GATA-1 Mediates Synergistic Expression of Megakaryocyte-Specific Genes through Cooperative DNA Binding
ABSTRACT Friend leukemia integration 1 (Fli-1) is a member of the Ets family of transcriptional activators that has been shown to… 
Highly Cited
2000
Highly Cited
2000
Identification of critical antigen-specific mechanisms in the development of immune thrombocytopenic purpura in mice.
The pathogenic effects of antiplatelet antibodies were investigated in mice. Monoclonal antibodies (mAbs) of different… 
Highly Cited
1998
Highly Cited
1998
Adhesion of Activated Platelets to Endothelial Cells: Evidence for a GPIIbIIIa-dependent Bridging Mechanism and Novel Roles for Endothelial Intercellular Adhesion Molecule 1 (ICAM-1), αvβ3 Integrin…
Although it has been reported that activated platelets can adhere to intact endothelium, the receptors involved have not been… 
Highly Cited
1998
Highly Cited
1998
Naturally occurring mutations in glycoprotein Ibalpha that result in defective ligand binding and synthesis of a truncated protein.
The platelet GPIb-V-IX complex is the receptor for the initial binding of von Willebrand factor (vWF) mediating platelet adhesion… 
Highly Cited
1996
Highly Cited
1996
Identification of a Mutation in a GATA Binding Site of the Platelet Glycoprotein Ibβ Promoter Resulting in the Bernard-Soulier Syndrome*
Bernard-Soulier Syndrome (BSS) is a rare congenital bleeding disorder due to absent or decreased expression of the glycoprotein… 
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