GMI-1070

Known as: Pan-Selectin Antagonist GMI-1070 
A synthetic, glycomimetic molecule and pan-selectin antagonist, with potential use in a vaso-occlusive crisis. Upon administration, GMI-1070 prevents… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2015
012320102015

Papers overview

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2016
2016
E-selectin is a cell-adhesion molecule of the vascular endothelium that promotes essential leukocyte rolling in the early… (More)
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2016
2016
Although production of hemoglobin S, the genetic defect that causes sickle cell disease (SCD), directly affects only red blood… (More)
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2015
2015
Treatment of vaso-occlusive crises (VOC) or events in sickle cell disease (SCD) remains limited to symptom relief with opioids… (More)
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Review
2013
Review
2013
Multiple myeloma (MM) is an incurable disease characterized by the proliferation of plasma cells. The survival in MM patients has… (More)
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2012
2012
Interactions between multiple myeloma (MM) cells and the BM microenvironment play a critical role in the pathogenesis of MM and… (More)
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2012
2012
Interactions between multiple myeloma (MM) cells and the BM microenvironment play a critical role in the pathogenesis of MM and… (More)
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Review
2012
Review
2012
Explorations of the therapeutic potential of heparin mimetics, anionic compounds that are analogues of glycosaminoglycans (GAGs… (More)
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2011
2011
In this issue of Blood, Gutsaeva et al describe an aptamer with high affinity for murine P-selectin and its efficacy in… (More)
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Highly Cited
2010
Highly Cited
2010
Leukocyte adhesion in the microvasculature influences blood rheology and plays a key role in vaso-occlusive manifestations of… (More)
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2010
2010
Thrombosis and ELISA optical density values in hospitalized patients with heparin-induced thrombocytopenia. from patients with… (More)
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