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GLI1 protein, human

Known as: GLI, Oncogene GLI, Zinc Finger Protein GLI1 
Zinc finger protein GLI1 (1106 aa, ~118 kDa) is encoded by the human GLI1 gene. This protein is involved in transcriptional regulation, cell… 
National Institutes of Health

Related topics

Related topics

17 relations
CYS2-HIS2 Zinc FingersCell NucleusDNA-Binding ProteinsFallopian Tubes

Broader (1)

Zinc Finger Protein GLI1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Highly Cited
2004
Highly Cited
2004
Hedgehog Signaling Pathway is a New Therapeutic Target for Patients with Breast Cancer
The Hedgehog (Hh) signaling pathway functions as an organizer in embryonic development. Genetic analysis has demonstrated a… 
Review
2002
Review
2002
Hedgehog–GLI signaling and the growth of the brain
The development of the vertebrate brain involves the creation of many cell types in precise locations and at precise times… 
Review
2000
Review
2000
The sonic hedgehog-patched-gli pathway in human development and disease.
Highly Cited
1999
Highly Cited
1999
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.
Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling in vertebrates. The question remains unanswered… 
Highly Cited
1999
Highly Cited
1999
Sonic Hedgehog-induced Activation of the Gli1Promoter Is Mediated by GLI3*
Drosophila transcription factorcubitus interruptus (Ci) and its co-activator CRE (cAMP response element)-binding protein (CBP… 
Highly Cited
1998
Highly Cited
1998
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.
Floor plate cells at the midline of the neural tube are specified by high-level activity of Sonic hedgehog (Shh) secreted by… 
Highly Cited
1998
Highly Cited
1998
The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants.
The expression of genes involved in the Sonic Hedgehog signalling pathway, including Shh, Ptc, Smo, Gli1, Gli2 and Gli3, were… 
Highly Cited
1997
Highly Cited
1997
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
Sporadic basal cell carcinoma (BCC) is the most common type of malignant cancer in fair-skinned adults. Familial BCCs and a… 
Highly Cited
1996
Highly Cited
1996
Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.
Sonic hedgehog is a secreted factor regulating patterning of the anterior-posterior axis in the developing limb. The signaling… 
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