FAQ

GLDC gene

Known as: glycine cleavage system protein P, GLYCINE CLEAVAGE SYSTEM P PROTEIN, NKH 
 

Topic mentions per year

Topic mentions per year

1966-2018
051019662018

Related topics

Related topics

2 relations
Glycine dehydrogenase (decarboxylating)Nonketotic Hyperglycinemia

Related mentions per year

Related mentions per year

1966-2018
1960198020002020
GLDC gene
Nonketotic Hyperglycinemia
Glycine dehydrogenase (decarboxylating)

Papers overview

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2014
2014
Variant non ketotic hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5.
Patients with nonketotic hyperglycinemia and deficient glycine cleavage enzyme activity, but without mutations in AMT, GLDC or… (More)
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Highly Cited
2012
Highly Cited
2012
Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis
Identification of the factors critical to the tumor-initiating cell (TIC) state may open new avenues in cancer therapy. Here we… (More)
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Highly Cited
2011
Highly Cited
2011
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics.
Major depressive disorder (MDD) is a common psychiatric disease. Selective serotonin reuptake inhibitors (SSRIs) are an important… (More)
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2007
2007
Deletion of glycine decarboxylase in Arabidopsis is lethal under nonphotorespiratory conditions.
The mitochondrial multienzyme glycine decarboxylase (GDC) catalyzes the tetrahydrofolate-dependent catabolism of glycine to 5,10… (More)
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2007
2007
Genomic deletion within GLDC is a major cause of non-ketotic hyperglycinaemia.
BACKGROUND Non-ketotic hyperglycinaemia (NKH) is an inborn error of metabolism characterised by accumulation of glycine in body… (More)
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2006
2006
Genetic heterogeneity of the GLDC gene in 28 unrelated patients with glycine encephalopathy
Glycine encephalopathy, or nonketotic hyperglycinaemia (NKH; Mckusick 238300) is a severe autosomal recessive disease due to a… (More)
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2006
2006
Comprehensive mutation analysis of GLDC, AMT, and GCSH in nonketotic hyperglycinemia.
Nonketotic hyperglycinemia (NKH) is an inborn error of metabolism characterized by accumulation of glycine in body fluids and… (More)
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Highly Cited
2004
Highly Cited
2004
Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype.
We investigated the frequency of promoter region CpG island methylation (CIM) of hMLH1, MGMT, MINT1, MINT2, and p16 and K-ras… (More)
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1995
1995
Inhibition of the glycine decarboxylase multienzyme complex by the host-selective toxin victorin.
Victoria blight of oats is caused by the fungus Cochliobolus victoriae. This fungus is pathogenic due to its ability to produce… (More)
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1982
1982
Mutants of the cruciferous plant Arabidopsis thaliana lacking glycine decarboxylase activity.
A mutant of Arabidopsis thaliana (L.) Heyn. (a small plant in the crucifer family) that lacks glycine decarboxylase activity… (More)
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