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Structure and function of Rubisco.
This review discusses Rubisco function in the context of structural variations at all levels--amino acid sequence, fold, tertiary and quaternary structure--with an evolutionary perspective and an emphasis on the structural features of the enzyme that may determine its function as a carboxylase. Expand
Femtosecond X-ray protein nanocrystallography
This work offers a new approach to structure determination of macromolecules that do not yield crystals of sufficient size for studies using conventional radiation sources or are particularly sensitive to radiation damage, by using pulses briefer than the timescale of most damage processes. Expand
Catalysis and regulation in Rubisco.
  • I. Andersson
  • Medicine, Biology
  • Journal of experimental botany
  • 19 June 2007
Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyses the incorporation of inorganic CO(2) into the organic molecules of life. Rubisco is extremely inefficient as a catalyst and itsExpand
Crystallographic analysis of ribulose 1,5-bisphosphate carboxylase from spinach at 2.4 A resolution. Subunit interactions and active site.
The X-ray structure of the quaternary complex of ribulose 1,5-bisphosphate carboxylase/oxygenase from spinach with CO2, Mg2+ and a reaction-intermediate analogue (CABP) has been determined andExpand
Single mimivirus particles intercepted and imaged with an X-ray laser
This work shows that high-quality diffraction data can be obtained with a single X-ray pulse from a non-crystalline biological sample, a single mimivirus particle, which was injected into the pulsed beam of a hard-X-ray free-electron laser, the Linac Coherent Light Source. Expand
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes
PENICILLIN antibiotics are all produced from fermentation-derived penicillins because their chemical synthesis is not commercially viable. The key step in penicillin biosynthesis, in which both theExpand
Structure of a cephalosporin synthase
The first crystal structure of a 2-oxoacid-dependent oxygenase is reported, obtained from merohedrally twinned crystals, and a model based on these structures is proposed for ferryl formation, which is common to many mononuclear ferrous enzymes. Expand
Large structures at high resolution: the 1.6 A crystal structure of spinach ribulose-1,5-bisphosphate carboxylase/oxygenase complexed with 2-carboxyarabinitol bisphosphate.
  • I. Andersson
  • Chemistry, Medicine
  • Journal of molecular biology
  • 31 May 1996
Analysis of the active site around the catalytically essential magnesium ion indicates that residues in the second liganding sphere of the metal play a role in fine-tuning the acid-base character and the position of the residues directly liganded to the metal. Expand
Three-dimensional reconstruction of the giant mimivirus particle with an x-ray free-electron laser.
A proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser is presented with a modified version of the expand, maximize and compress algorithm. Expand
First Crystal Structure of Rubisco from a Green Alga,Chlamydomonas reinhardtii *
The crystal structure of Rubisco (ribulose 1,5-bisphosphate carboxylase/oxygenase) from the unicellular green alga Chlamydomonas reinhardtii has been determined to 1.4 Å resolution. Overall, theExpand