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GGTI 297

Known as: GGTI-297 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Benzamides

Papers overview

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2013
2013
A Homology Based Model and Virtual Screening of Inhibitors for Human Geranylgeranyl Transferase 1 (GGTase1)
Protein prenylation is a post translational modification that is indispensable for Ras–Rho mediated tumorigenesis. In mammals… 
2007
2007
RhoA Prenylation Inhibitor Produces Relaxation of Tonic Smooth Muscle of Internal Anal Sphincter
RhoA prenylation is a critical step for the translocation of RhoA to the membrane and its activation in response to agonist… 
1999
1999
Cytotoxic Agents Cisplatin , Taxol , and Gemcitabine Geranylgeranyltransferase I : Combination Therapy with the Peptidomimetic Inhibitors of Farnesyltransferase and Antitumor Efficacy of a Novel…
Ras malignant transformation requires posttranslational modification by farnesyltransferase (FTase). Here we report on the design… 
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