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GGTI-2133

National Institutes of Health

Related topics

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4 relations

Broader (3)

ImidazolesLeucineNaphthalenes
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Isoprenylation and NET formation in acute pancreatitis
Acute Pancreatitis (AP) is an inflammation disease that characterized by activation of protease and the innate immune system… 
2014
2014
Involvement of protein isoprenylation in neuropathic pain induced by sciatic nerve injury in mice
2014
2014
Theoretical studies on binding and specificity mechanisms of farnesyltransferase (FTase) and geranylgeranyltransferase type-I (GGTase-I) inhibitors by molecular modeling.
Farnesyltransferase (FTase) and geranylgeranyltransferase type-I (GGTase-I) are two members of protein prenyltransferases, which… 
2013
2013
Pharmacological modulation of geranylgeranyltransferase and farnesyltransferase attenuates opioid withdrawal in vivo and in vitro
2013
2013
Inhibition of geranylgeranyltransferase attenuates neutrophil accumulation and tissue injury in severe acute pancreatitis
Leukocyte infiltration and acinar cell necrosis are hallmarks of severe AP, but the signaling pathways regulating inflammation… 
2013
2013
Geranylgeranyl Transferase Regulates Streptococcal M1 Protein-Induced CXC Chemokine Formation and Neutrophil Recruitment in the Lung
ABSTRACT Streptococcal toxic shock syndrome is most frequently associated with Streptococcus pyogenes of the M1 serotype… 
2010
2010
A distinct cAMP signaling pathway mediates the odorant receptor-instructed coarse targeting of axons
2010
2010
Biosynthesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation
2009
2009
Inhibition of geranylgeranyltransferase inhibits bronchial smooth muscle hyperresponsiveness in mice.
Recent studies revealed an involvement of RhoA/Rho-kinase in the contraction of bronchial smooth muscle (BSM), and this pathway… 
2008
2008
Mevalonate sensitizes the nociceptive transmission in the mouse spinal cord
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