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GEN1 protein, human

Known as: EC 3.1.-.-, Gen Endonuclease Homolog 1, Flap Endonuclease GEN Homolog 1 
Flap endonuclease GEN homolog 1 (908 aa, ~103 kDa) is encoded by the human GEN1 gene. This protein plays a role in homologous recombination and DNA… Expand
National Institutes of Health

Papers overview

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2017
2017
Significance Holliday junction resolvases are required for the resolution of recombination intermediates to ensure proper… Expand
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2012
2012
The maintenance of genomic stability requires accurate genome replication, repair of DNA damage, and the precise segregation of… Expand
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Highly Cited
2010
Highly Cited
2010
DNA double-strand breaks (DSBs) can be repaired by homologous recombination (HR), which can involve Holliday junction (HJ… Expand
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2009
2009
  • Stephen C West
  • Biochemical Society transactions
  • 2009
  • Corpus ID: 206153627
Four-way DNA intermediates, known as Holliday junctions, are formed during mitotic and meiotic recombination, and their efficient… Expand
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