APEX2 protein, human

Known as: AP Endonuclease XTH2, APEXL2, APEX nuclease (apurinic-apyrimidinic endonuclease) 2 protein, human 
DNA-(apurinic or apyrimidinic site) lyase 2 (518 aa, ~57 kDa) is encoded by the human APEX2 gene. This protein is involved in DNA repair.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
05101519802017

Papers overview

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2013
2013
Immunoglobulin (Ig) class switch recombination (CSR) is initiated by activation-induced cytidine deaminase (AID) that catalyzes… (More)
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2013
2013
The Crc protein has been shown to mediate catabolite repression control in Pseudomonas, leading to a preferential assimilation of… (More)
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2009
2009
Resistance to platinum is a major limitation for the treatment of ovarian cancer. In an effort to overcome the platinum… (More)
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2008
2008
BACKGROUND AND AIM Apurinic/apyrimidinic endonuclease-1 (APE-1) is a key enzyme in DNA base excision repair (BER), linked to… (More)
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2007
2007
The individual steps in single-nucleotide base excision repair (SN-BER) are coordinated to enable efficient repair without… (More)
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2004
2004
BACKGROUND & AIMS Helicobacter pylori infection causes inflammation, accumulation of reactive oxygen species, and oxidative DNA… (More)
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Highly Cited
1999
Highly Cited
1999
Previously we showed that a mismatch repair (MMR)-deficient cell line, HCT116 (hMLH1 mut), unlike a MMR wild-type cell line… (More)
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1999
1999
The apurinic/apyrimidinic endonucleases (APE) contain several highly conserved sequence motifs. The glutamic acid residue in a… (More)
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Highly Cited
1997
Highly Cited
1997
The structure of the major human apurinic/ apyrimidinic endonuclease (HAP1) has been solved at 2.2 A resolution. The enzyme… (More)
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