Holliday Junction Resolvases
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Four-way DNA intermediates, called Holliday junctions (HJs), can form during meiotic and mitotic recombination, and their removal… Expand DNA double-strand breaks (DSBs) and other lesions occur frequently during cell growth and in meiosis. These are often repaired by… Expand Four-way DNA intermediates, known as Holliday junctions, are formed during mitotic and meiotic recombination, and their efficient… Expand ABSTRACT Piv, a unique prokaryotic site-specific DNA invertase, is related to transposases of the insertion elements from the… Expand Genetic recombination is a critical cellular process that promotes evolutionary diversity, facilitates DNA repair and underpins… Expand Endonucleolytic cleavage of Holliday junctions is important in recombination and replication. Mus81 proteins in yeasts and humans… Expand Holliday junction resolvases (HJRs) are key enzymes of DNA recombination. A detailed computer analysis of the structural and… Expand BACKGROUND
Members of the structurally-related superfamily of enzymes that includes RNase H, RuvC resolvase, MuA transposase, and… Expand E. coli RuvC protein resolves Holliday junctions during genetic recombination and postreplication repair. Using small synthetic… Expand An assay was developed that detected DNA cruciform cutting endonuclease activity in crude extracts of Saccharomyces cerevisiae. A… Expand