Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

GE 2770

Known as: GE-2270, GE2270 
 
National Institutes of Health

Related topics

Related topics

1 relation
GE 2270 A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Heterologous Expression of the Thiopeptide Antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor Requires Deletion of Ribosomal Genes from the Expression Construct
GE2270 is a thiopeptide antibiotic generated by extensive posttranslational modifications of a ribosomally generated precursor… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
2013
2013
Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.
Thiopeptides are ribosomally synthesized, posttranslationally modified peptides with potent activity against Gram-positives… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2011
2011
In vitro and in vivo activities of novel, semisynthetic thiopeptide inhibitors of bacterial elongation factor Tu.
Recently, we identified aminothiazole derivatives of GE2270 A. These novel semisynthetic congeners, like GE2270 A, target the… Expand
Is this relevant?
2011
2011
4-Aminothiazolyl analogues of GE2270 A: antibacterial lead finding.
4-Aminothiazolyl analogues of the antibacterial natural product GE2270 A (1) were designed, synthesized, and evaluated for gram… Expand
Is this relevant?
2011
2011
Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.
4-Aminothiazolyl analogues of the antibiotic natural product GE2270 A (1) were designed, synthesized, and optimized for their… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
2003
2003
Changes in GE2270 antibiotic production in Planobispora rosea through modulation of methylation metabolism.
Thiazolylpeptide GE2270 is a potent antibiotic inhibiting protein synthesis in Gram-positive bacteria. It is produced as a… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
1996
1996
An elongation factor Tu (EF-Tu) resistant to the EF-Tu inhibitor GE2270 in the producing organism Planobispora rosea.
Using a cell-free protein-synthesis system, we have established that the elongation factor (EF) Tu (EF-Tu) of the actinomycete… Expand
Is this relevant?
1991
1991
Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. II. Structure elucidation.
GE2270 A, produced by Planobispora rosea ATCC 53773, inhibits Gram-positive bacteria and anaerobes by acting on the bacterial… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1991
1991
Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. I. Isolation and characterization.
A novel antibiotic, GE2270 A, was isolated from the fermentation broth of a strain of Planobispora rosea. The product was found… Expand
  • table 3
  • table 1
  • figure 1
  • table 5
  • figure 2
Is this relevant?
1991
1991
New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu.
The new thiazolyl peptide antibiotic GE2270 A, isolated from Planobispora rosea strain ATCC 53773, is shown to inhibit bacterial… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE