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GE 2770
Known as:
GE-2270
, GE2270
National Institutes of Health
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Related topics
Related topics
1 relation
GE 2270 A
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Heterologous Expression of the Thiopeptide Antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor Requires Deletion of Ribosomal Genes from the Expression Construct
K. Flinspach
,
Claudia Kapitzke
,
A. Tocchetti
,
M. Sosio
,
A. Apel
PloS one
2014
Corpus ID: 3667109
GE2270 is a thiopeptide antibiotic generated by extensive posttranslational modifications of a ribosomally generated precursor…
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2013
2013
Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.
A. Tocchetti
,
S. Maffioli
,
+5 authors
S. Donadio
Chemistry & biology
2013
Corpus ID: 23580303
2011
2011
Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.
M. LaMarche
,
J. Leeds
,
+18 authors
Donghui Yu
Journal of medicinal chemistry
2011
Corpus ID: 6730217
4-Aminothiazolyl analogues of the antibiotic natural product GE2270 A (1) were designed, synthesized, and optimized for their…
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2011
2011
4-Aminothiazolyl analogues of GE2270 A: antibacterial lead finding.
M. LaMarche
,
J. Leeds
,
+8 authors
B. Wang
Journal of medicinal chemistry
2011
Corpus ID: 31452342
4-Aminothiazolyl analogues of the antibacterial natural product GE2270 A (1) were designed, synthesized, and evaluated for gram…
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2008
2008
Concise total synthesis of the thiazolyl peptide antibiotic GE2270 A.
Ó. Delgado
,
H. Müller
,
T. Bach
Chemistry
2008
Corpus ID: 28525802
The potent antibiotic thiazolylpeptide GE2270 A was synthesized starting from N-tert-butyloxycarbonyl protected valine in a…
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2006
2006
Synthesis and configurational assignment of the amino alcohol in the eastern fragment of the GE2270 antibiotics by regio- and stereoselective addition of 2-metalated 4-bromothiazoles to alpha-chiral…
Ó. Delgado
,
Golo Heckmann
,
H. Müller
,
T. Bach
The Journal of organic chemistry
2006
Corpus ID: 23656291
A synthesis of the eastern fragment of the thiazole peptide GE2270 A (1) has been developed. The synthetic approach relies on the…
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1993
1993
In vitro antimicrobial activity of a new antibiotic, MDL 62,879 (GE2270 A)
B. Goldstein
,
M. Berti
,
F. Ripamonti
,
A. Resconi
,
R. Scotti
,
M. Denaro
Antimicrobial Agents and Chemotherapy
1993
Corpus ID: 26472528
MDL 62,879 (GE2270 A) is a new peptide antibiotic that inhibits protein synthesis through an interaction with elongation factor…
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Highly Cited
1991
Highly Cited
1991
Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. I. Isolation and characterization.
E. Selva
,
G. Beretta
,
+7 authors
B. Goldstein
The Journal of antibiotics
1991
Corpus ID: 40343736
A novel antibiotic, GE2270 A, was isolated from the fermentation broth of a strain of Planobispora rosea. The product was found…
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1991
1991
Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. II. Structure elucidation.
J. Kettenring
,
L. Colombo
,
+5 authors
E. Selva
The Journal of antibiotics
1991
Corpus ID: 43739179
GE2270 A, produced by Planobispora rosea ATCC 53773, inhibits Gram-positive bacteria and anaerobes by acting on the bacterial…
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Highly Cited
1991
Highly Cited
1991
New antibiotic that acts specifically on the GTP‐bound form of elongation factor Tu.
P. H. Anborgh
,
A. Parmeggiani
The EMBO journal
1991
Corpus ID: 20921859
The new thiazolyl peptide antibiotic GE2270 A, isolated from Planobispora rosea strain ATCC 53773, is shown to inhibit bacterial…
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