GDP-dissociation inhibitor activity

Known as: GDI 
Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding. [GOC:mah]
National Institutes of Health

Papers overview

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Review
2005
Review
2005
The GDP dissociation inhibitors (GDIs) are pivotal regulators of Rho GTPase function. GDIs control the access of Rho GTPases to… (More)
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Highly Cited
2003
Highly Cited
2003
Human cells contain more than 60 small G proteins of the Rab family, which are localized to the surfaces of distinct membrane… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE Rho family members are small GTPases that are known to regulate malignant transformation and motility of cancer cells… (More)
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Highly Cited
2002
Highly Cited
2002
The proper function of Rho GTPases requires precise spatial and temporal regulation of effector interactions. Integrin-mediated… (More)
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Highly Cited
2001
Highly Cited
2001
The Rho-GDP guanine nucleotide dissociation inhibitor (GDI) complexes with the GDP-bound form of Rho and inhibits its activation… (More)
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1994
1994
We have previously isolated rho GDP dissociation inhibitor (rho DGI) from bovine brain and characterized it. Bovine rho GDI is a… (More)
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Highly Cited
1994
Highly Cited
1994
MAJOR histocompatibility complex (MHC) class I and class II molecules bind immunogenic peptides and present them to lymphocytes… (More)
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Highly Cited
1993
Highly Cited
1993
The Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation… (More)
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Highly Cited
1993
Highly Cited
1993
Evidence is accumulating that the rho family, a member of the ras p21-related small GTP-binding protein superfamily, regulates… (More)
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Highly Cited
1993
Highly Cited
1993
Evidence is accumulating that rho p21, a ras p21-related small GTP-binding protein (G protein), regulates the actomyosin system… (More)
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