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GDI1 gene

Known as: GDI1, OLIGOPHRENIN 2, RABGDIA 
National Institutes of Health

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Related topics

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ARHGDIA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
Inhibitors of apoptosis proteins (IAPs) are a highly conserved class of multifunctional proteins. Rac1 is a well‐studied Rho… 
Highly Cited
2009
Highly Cited
2009
Dosage-dependent severity of the phenotype in patients with mental retardation due to a recurrent copy-number gain at Xq28 mediated by an unusual recombination.
Highly Cited
2009
Highly Cited
2009
Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimer's disease and mild cognitive impairment…
Alzheimer's disease (AD) is the most common type of dementia, comprising 60-80% of all reported cases, and currently affects 5.2… 
Highly Cited
2006
Highly Cited
2006
In vivo dynamics of Rac-membrane interactions.
The small GTPase Rac cycles between the membrane and the cytosol as it is activated by nucleotide exchange factors (GEFs) and… 
2006
2006
Phosphorylation of RhoGDI by p21-activated kinase 1.
Highly Cited
2004
Highly Cited
2004
Mice deficient for the synaptic vesicle protein Rab3a show impaired spatial reversal learning and increased explorative activity but none of the behavioral changes shown by mice deficient for the…
Rab proteins are small GTPases involved in intracellular trafficking. Among the 60 different Rab proteins described in mammals… 
Highly Cited
2002
Highly Cited
2002
RhoGDI2 is an invasion and metastasis suppressor gene in human cancer.
To discover novel metastasis suppressor genes that are clinically relevant in common human cancers, we used isogenic human… 
Highly Cited
2002
Highly Cited
2002
Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice.
Non-specific mental retardation (NSMR) is a common human disorder characterized by mental handicap as the only clinical symptom… 
Highly Cited
2000
Highly Cited
2000
PRA1 Inhibits the Extraction of Membrane-bound Rab GTPase by GDI1*
Rab is a family of small Ras-like GTPases regulating intracellular vesicle transport. We have previously reported that prenylated… 
Review
1999
Review
1999
XLMR genes: update 1998.
Since the Seventh Fragile X and XLMR Mental Retardation (XLMR) Workshop in 1995, the genes for Coffin-Lowry, Mohr-Tranebjaerg… 
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