GDI1 gene

Small-molecule inhibitors are an attractive therapeutic approach for most types of human cancers. SKLB-163, a novel benzothiazole… Expand

Inhibitors of apoptosis proteins (IAPs) are a highly conserved class of multifunctional proteins. Rac1 is a well-studied Rho… Expand

Alzheimer's disease (AD) is the most common type of dementia, comprising 60-80% of all reported cases, and currently affects 5.2… Expand

The small GTPase Rac cycles between the membrane and the cytosol as it is activated by nucleotide exchange factors (GEFs) and… Expand

Rho GTPase activation is partially regulated at the level of guanine nucleotide dissociation inhibitors, or GDIs. The binding of… Expand

Rab proteins are small GTPases involved in intracellular trafficking. Among the 60 different Rab proteins described in mammals… Expand

Non-specific mental retardation (NSMR) is a common human disorder characterized by mental handicap as the only clinical symptom… Expand

To discover novel metastasis suppressor genes that are clinically relevant in common human cancers, we used isogenic human… Expand

Rab is a family of small Ras-like GTPases regulating intracellular vesicle transport. We have previously reported that prenylated… Expand

Since the Seventh Fragile X and XLMR Mental Retardation (XLMR) Workshop in 1995, the genes for Coffin-Lowry, Mohr-Tranebjaerg… Expand