Skip to search formSkip to main contentSkip to account menu

GATA1 gene

Known as: GATA binding protein 1, NF-E1, NFE1 
This gene is involved in erythropoiesis and transcriptional activation.
National Institutes of Health

Related topics

Related topics

11 relations
ErythropoiesisGATA1 Gene MutationGATA1 Transcription FactorGATA1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization.
Endomitosis is a unique form of cell cycle used by megakaryocytes, in which the latter stages of mitosis are bypassed so that the… 
Highly Cited
2004
Highly Cited
2004
Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia.
Association of GATA-1 and its cofactor Friend of GATA-1 (FOG-1) is essential for erythroid and megakaryocyte development. To… 
Highly Cited
1999
Highly Cited
1999
The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor alpha-chain gene.
Key regulatory regions necessary for the expression of the gene encoding FcepsilonRI alpha-chain, a component of the high… 
Highly Cited
1996
Highly Cited
1996
Characterization of the Duffy gene promoter: evidence for tissue-specific abolishment of expression in Fy(a-b-) of black individuals.
We have previously identified a novel first exon of Duffy gene and two inverse GATA motifs in the 600 bp 5' flanking region. The… 
Highly Cited
1995
Highly Cited
1995
The expression pattern of erythrocyte/megakaryocyte-related transcription factors GATA-1 and the stem cell leukemia gene correlates with hematopoietic differentiation and is associated with outcome…
To understand the clinical implications of transcription factors and their biologic roles during cellular differentiation in the… 
Highly Cited
1993
Highly Cited
1993
Characterization of the Promoter Region of the Human c‐kit Proto‐oncogene
The c‐kit proto‐oncogene encodes a tyrosine kinase receptor for stem cell factor and plays a critical role in the growth and… 
Highly Cited
1993
Highly Cited
1993
Transactivation of GATA-1 promoter with ETS1, ETS2 and ERGB/Hu-FLI-1 proteins: stabilization of the ETS1 protein binding on GATA-1 promoter sequences by monoclonal antibody.
Ets family proteins activate transcription via binding to the GGAA core sequence located in the promoter/enhancer elements of… 
Highly Cited
1991
Highly Cited
1991
GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene.
Highly Cited
1991
Highly Cited
1991
Structure and promoter activity of the gene for the erythroid transcription factor GATA-1.
We have cloned the gene for the chicken erythroid transcription factor GATA-1 (formerly Eryf1, NF-E1, or GF-1). The gene is… 
Highly Cited
1991
Highly Cited
1991
An erythroid specific enhancer upstream to the gene encoding the cell-type specific transcription factor GATA-1.
The transcription factor GATA-1 is expressed in a subset of hemopoietic cells, where it mediates the cell-type specific… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)