GART protein, human

Known as: EC 6.3.3.1, Phosphoribosylglycinamide Synthetase, Phosphoribosylamine--Glycine Ligase 
Trifunctional purine biosynthetic protein adenosine-3 (1010 aa, ~108 kDa) is encoded by the human GART gene. This protein is involved in the de novo… (More)

Topic mentions per year

Topic mentions per year

1969-2017
0246819692017

Papers overview

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2011
2011
Pemetrexed (PEM), a multitargeted antifolate with manageable toxicity, is active against non-squamous non-small cell lung cancer… (More)
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2010
2010
Human purine de novo synthesis pathway contains several multi-functional enzymes, one of which, tri-functional GART, contains… (More)
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2009
2009
Mutations in several steps of de novo purine synthesis lead to human inborn errors of metabolism often characterized by mental… (More)
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2006
2006
We are presenting a software development framework called OSGART for Rapid Application Developement (RAD) in the domain of Mixed… (More)
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2003
2003
p53 is believed to sense cellular ribonucleotide depletion in the absence of DNA strand breaks and to respond by imposition of a… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To determine the short-term effects of using genotypic antiretroviral resistance testing (GART) with expert advice in… (More)
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2000
2000
The SON gene, which maps to human chromosome 21q22.1-q22.2, encodes a novel regulatory protein. Here we describe the organization… (More)
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Highly Cited
1997
Highly Cited
1997
N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl ]-benzoyl]-L-glutamic acid (LY231514) is a novel pyrrolo… (More)
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1997
1997
Purines are critical for energy metabolism, cell signalling and cell reproduction. Nevertheless, little is known about the… (More)
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1991
1991
Two Yeast Artificial Chromosomes (YACs) were isolated each with a full-length copy of the human gene that encodes the… (More)
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