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GABRA3 gene

Known as: gamma-aminobutyric acid type A receptor alpha3 subunit, GABRA3, Gamma-Aminobutyric Acid Type A Receptor Alpha3 Subunit Gene 
This gene is involved in neurotransmission and ligand-gated ion transport.
National Institutes of Health

Related topics

Related topics

7 relations
GABRE geneHomo sapiensIonophore activityLigand Binding
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer
BackgroundMicroRNAs (miRNAs) can act as oncogenes or tumor suppressors by controlling cell proliferation, differentiation… Expand
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2017
2017
Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features
Genetic epilepsies are caused by mutations in a range of different genes, many of them encoding ion channels, receptors or… Expand
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Highly Cited
2016
Highly Cited
2016
The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
Metastasis is a critical event affecting breast cancer patient survival. To identify molecules contributing to the metastatic… Expand
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2010
2010
Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice
The Tail Suspension Test (TST), which measures behavioral despair, is widely used as an animal model of human depressive… Expand
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Highly Cited
2009
Highly Cited
2009
GABAA Receptor Downregulation in Brains of Subjects with Autism
Gamma-aminobutyric acid A (GABAA) receptors are ligand-gated ion channels responsible for mediation of fast inhibitory action of… Expand
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Highly Cited
2008
Highly Cited
2008
Developmental Modulation of GABAA Receptor Function by RNA Editing
Adenosine-to-inosine (A-to-I) editing of RNA transcripts is an increasingly recognized cellular strategy to modulate the function… Expand
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2008
2008
Gamma-aminobutyric acid promotes human hepatocellular carcinoma growth through overexpressed gamma-aminobutyric acid A receptor alpha 3 subunit.
AIM To investigate the expression pattern of gamma-aminobutyric acid A (GABAA) receptors in hepatocellular carcinoma (HCC) and… Expand
Highly Cited
2008
Highly Cited
2008
Pathway-based association analysis of genome-wide screening data suggest that genes associated with the &ggr;-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced…
Objective Neuroleptic-induced tardive dyskinesia (TD) is an involuntary movement disorder that develops in patients who have… Expand
Highly Cited
2002
Highly Cited
2002
Excess of allele1 for α3 subunit GABA receptor gene (GABRA3) in bipolar patients: a multicentric association study
The available data from preclinical and pharmacological studies on the role of gamma amino butyric acid (GABA) support the… Expand
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1989
1989
Physical linkage of a GABAA receptor subunit gene to the DXS374 locus in human Xq28.
We report the physical linkage of the gene encoding one of the subunits of the GABAA receptor (GABRA3) to the polymorphic locus… Expand
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