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GABRA3 gene

Known as: gamma-aminobutyric acid type A receptor alpha3 subunit, GABRA3, Gamma-Aminobutyric Acid Type A Receptor Alpha3 Subunit Gene 
This gene is involved in neurotransmission and ligand-gated ion transport.
National Institutes of Health

Related topics

Related topics

7 relations
GABRE geneHomo sapiensIonophore activityLigand Binding
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer
BackgroundMicroRNAs (miRNAs) can act as oncogenes or tumor suppressors by controlling cell proliferation, differentiation… Expand
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2016
2016
The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
Metastasis is a critical event affecting breast cancer patient survival. To identify molecules contributing to the metastatic… Expand
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2013
2013
Analysis of the effects of rare variants on splicing identifies alterations in GABAA receptor genes in autism spectrum disorder individuals
A large-scale sequencing screen of X-linked synaptic genes in individuals with autism spectrum disorder (ASD) or schizophrenia… Expand
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2010
2010
Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice
The Tail Suspension Test (TST), which measures behavioral despair, is widely used as an animal model of human depressive… Expand
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2010
2010
Age-related gene-specific changes of A-to-I mRNA editing in the human brain
A-to-I editing is an adenosine-to-inosine modification of mRNA particularly widespread in the human brain, where it affects… Expand
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Highly Cited
2008
Highly Cited
2008
GABAA Receptor Downregulation in Brains of Subjects with Autism
Gamma-aminobutyric acid A (GABAA) receptors are ligand-gated ion channels responsible for mediation of fast inhibitory action of… Expand
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Highly Cited
2008
Highly Cited
2008
Developmental modulation of GABA(A) receptor function by RNA editing.
Adenosine-to-inosine (A-to-I) editing of RNA transcripts is an increasingly recognized cellular strategy to modulate the function… Expand
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Highly Cited
2008
Highly Cited
2008
Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced…
OBJECTIVE Neuroleptic-induced tardive dyskinesia (TD) is an involuntary movement disorder that develops in patients who have… Expand
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2002
2002
Excess of allele1 for α3 subunit GABA receptor gene (GABRA3) in bipolar patients: a multicentric association study
The available data from preclinical and pharmacological studies on the role of gamma amino butyric acid (GABA) support the… Expand
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Highly Cited
2000
Highly Cited
2000
Mutation screening in Rett syndrome patients.
Rett syndrome (RTT) was first described in 1966. Its biological and genetic foundations were not clear until recently when Amir… Expand
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