G1 Phase Cell Cycle Checkpoints

Known as: G1 Phase Checkpoint, Checkpoints, G1 Phase, Checkpoint, G1 Phase 
Regulatory signaling systems that control the progression of the CELL CYCLE through the G1 PHASE and allow transition to S PHASE when the cells are… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The stringent regulation of cell cycle progression helps to maintain genetic stability in cells. MicroRNAs (miRNAs) are critical… (More)
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2008
2008
Genotoxic stress activates the phosphatidylinositol 3-kinase-like kinases (PIKKs) that phosphorylate proteins involved in cell… (More)
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2008
2008
Several DNA damage checkpoint factors form nuclear foci in response to ionizing radiation (IR). Although the number of the… (More)
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Highly Cited
2007
Highly Cited
2007
Phosphorylation of histone H2A or H2AX is an early and sensitive marker of DNA damage in eukaryotic cells, although mutation of… (More)
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2007
2007
Non-homologous end joining (NHEJ) and homologous recombination (HR) are two pathways that can compete or cooperate for DNA double… (More)
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2002
2002
Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of cancer. In the absence of other genetic alterations… (More)
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Highly Cited
2001
Highly Cited
2001
Premature chromatin condensation (PCC) is a hallmark of mammalian cells that begin mitosis before completing DNA replication… (More)
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Highly Cited
1996
Highly Cited
1996
The commitment of mammalian cells in late G1 to replicate the genome and divide in response to mitogenic growth factors operating… (More)
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Highly Cited
1995
Highly Cited
1995
p21CIP1/WAF1 is a CDK inhibitor regulated by the tumor suppressor p53 and is hypothesized to mediate G1 arrest. p53 has been… (More)
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Highly Cited
1995
Highly Cited
1995
We have examined the effect of abrogation of the G2 checkpoint on the radiosensitivity of G1 checkpoint-proficient and G1… (More)
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