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G-Quadruplexes

Known as: G Quadruplexes, Guanine Quadruplexes, G-Quadruplexes DNA 
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen… 
National Institutes of Health

Related topics

Related topics

5 relations
DNA, CruciformGuanine-Tetradsaspects of radiation effects

Narrower (2)

G-Quadruplexes, DNAG-Quadruplexes, RNA

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
RNA G-quadruplexes and their potential regulatory roles in translation
ABSTRACT DNA guanine (G)-rich 4-stranded helical nucleic acid structures called G-quadruplexes (G4), have been extensively… 
Review
2012
Review
2012
Sequence, Stability, and Structure of G‐Quadruplexes and Their Interactions with Drugs
Although DNA is most widely known for its ability to store and pass along genetic information, the discovery of G‐quadruplex… 
Review
2010
Review
2010
Interaction of metal complexes with G-quadruplex DNA.
Guanine-rich sequences of DNA can assemble into tetrastranded structures known as G-quadruplexes. It has been suggested that… 
Highly Cited
2009
Highly Cited
2009
Unstable taxa in cladistic analysis: identification and the assessment of relevant characters
A common problem in phylogenetic analysis is the presence of unstable taxa that are depicted in multiple positions in optimal… 
Highly Cited
2008
Highly Cited
2008
The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex–interactive agents
Previous studies on the functional analysis of the human vascular endothelial growth factor (VEGF) promoter using the full-length… 
Highly Cited
2007
Highly Cited
2007
Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes
Parallel tetramolecular quadruplexes may be formed with short oligodeoxynucleotides bearing a block of three or more guanines. We… 
Highly Cited
2005
Highly Cited
2005
Guanine quartet networks stabilized by cooperative hydrogen bonds.
Hydrogen bonding between DNA or RNA bases is one of the main interactions that determines the conformation and biochemical… 
Highly Cited
2000
Highly Cited
2000
Toward Artificial Ion Channels: A Lipophilic G-Quadruplex
Single crystals of a lipophilic G-quadruplex formed by 5‘-tert-butyl-dimethylsilyl-2‘,3‘,-di-O-isopropylidene G 2 were obtained… 
Highly Cited
1999
Highly Cited
1999
2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase.
Telomerase is a major new target for the rational design of novel anticancer agents. We have previously identified anthraquinone… 
Highly Cited
1990
Highly Cited
1990
A sodium-potassium switch in the formation of four-stranded G4-DNA
Single-stranded complex guanine-rich DNA sequences from chromosomal telomeres and else-where can associate to form stable… 
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