G-Quadruplexes

Known as: G Quadruplexes, Guanine Quadruplexes, G-Quadruplexes DNA 
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
05010019892018

Papers overview

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2016
2016
G quadruplexes (G4s) can present potent blocks to DNA replication. Accurate and timely replication of G4s in vertebrates requires… (More)
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2014
2014
Spinach is an in vitro-selected RNA aptamer that binds a GFP-like ligand and activates its green fluorescence. Spinach is thus an… (More)
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Highly Cited
2013
Highly Cited
2013
The G-quadruplex is an alternative DNA structural motif that is considered to be functionally important in the mammalian genome… (More)
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Highly Cited
2012
Highly Cited
2012
T loops and telomeric G-quadruplex (G4) DNA structures pose a potential threat to genome stability and must be dismantled to… (More)
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Highly Cited
2011
Highly Cited
2011
G-quadruplex (G4) DNA structures are extremely stable four-stranded secondary structures held together by noncanonical G-G base… (More)
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2010
2010
The 3' strand of telomeres is composed of tandem repeats of short G-rich sequences which protrude as single-stranded DNA… (More)
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2010
2010
Tandem stretches of guanines can associate in hydrogen-bonded arrays to form G-quadruplexes, which are stabilized by K(+) ions… (More)
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Highly Cited
2009
Highly Cited
2009
In budding yeast, the Pif1 DNA helicase is involved in the maintenance of both nuclear and mitochondrial genomes, but its role in… (More)
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2009
2009
Since the outbreak of severe acute respiratory syndrome (SARS) in 2003, the three-dimensional structures of several of the… (More)
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Highly Cited
1990
Highly Cited
1990
Single-stranded complex guanine-rich DNA sequences from chromosomal telomeres and elsewhere can associate to form stable parallel… (More)
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