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G-Quadruplexes

Known as: G Quadruplexes, Guanine Quadruplexes, G-Quadruplexes DNA 
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen… 
National Institutes of Health

Related topics

Related topics

5 relations
DNA, CruciformGuanine-Tetradsaspects of radiation effects

Narrower (2)

G-Quadruplexes, DNAG-Quadruplexes, RNA

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Implication of the solvent effect, metal ions and topology in the electronic structure and hydrogen bonding of human telomeric G-quadruplex DNA.
We present a first-principles density functional study elucidating the effects of solvent, metal ions and topology on the… 
Highly Cited
2010
Highly Cited
2010
Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.
A new biomolecular device for investigating the interactions of ligands with constrained DNA quadruplex topologies, using surface… 
Highly Cited
2007
Highly Cited
2007
Polarizability of G4-DNA observed by electrostatic force microscopy measurements.
G4-DNA, a quadruple helical motif of stacked guanine tetrads, is stiffer and more resistant to surface forces than double… 
2007
2007
Pyrene excimer fluorescence as a probe for parallel G-quadruplex formation.
The formation and properties of G-quadruplex structures from short single-strand oligonucleotide conjugates possessing two to… 
2007
2007
Allosteric control of self-assembly: modulating the formation of guanine quadruplexes through orthogonal aromatic interactions.
Review
2006
Review
2006
Fluorescence resonance energy transfer in the studies of guanine quadruplexes.
A guanine (G)-quadruplex DNA motif has recently emerged as a biologically important structure that is believed to interfere with… 
Highly Cited
2005
Highly Cited
2005
Covalent ligation studies on the human telomere quadruplex
Recent X-ray crystallographic studies on the human telomere sequence d[AGGG(TTAGGG)3] revealed a unimolecular, parallel… 
Highly Cited
2003
Highly Cited
2003
Lipophilic G-quadruplexes are self-assembled ion pair receptors, and the bound anion modulates the kinetic stability of these complexes.
With an eye toward the eventual selective modification of noncovalent structures, we used ESI-MS, X-ray crystallography, and NMR… 
Highly Cited
2002
Highly Cited
2002
Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay.
The telomeric repeat amplification protocol (TRAP) is commonly used to evaluate telomerase activity in tissues or cell extracts… 
1989
1989
A G4-DNA/B-DNA junction at codon 12 of c-Ha-ras is actively and asymmetrically methylated by DNA(cytosine-5)methyltransferase.
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