Skip to search formSkip to main contentSkip to account menu

Fumarate Hydratase, Mitochondrial, human

Known as: FH, Fumarate Hydratase, Mitochondrial, EC 4.2.1.2 
Fumarate hydratase, mitochondrial (510 aa, ~55 kDa) is encoded by the human FH gene. This protein plays a role in the meditation of the citric acid… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell RespirationCitrate Cycle (TCA Cycle) PathwayCitric Acid CycleEnzyme Gene

Broader (1)

MTHFD1L gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Enhanced protective antibody to a mutant meningococcal factor H-binding protein with low-factor H binding.
Meningococcal factor H-binding protein (FHbp) is an antigen in 2 serogroup B meningococcal vaccines. FHbp specifically binds… 
2013
2013
fH-dependent complement evasion by disease-causing meningococcal strains with absent fHbp genes or frameshift mutations.
2008
2008
A cancer‐predisposing “hot spot” mutation of the fumarase gene creates a dominant negative protein
The Fumarase (Fumarate Hydratase, FH) is a tumor suppressor gene whose germline heterozygous mutations predispose to hereditary… 
2007
2007
Subcellular localization of fumarase in mammalian cells and tissues
Fumarase, a mitochondrial matrix protein, is previously indicated to be present in substantial amounts in the cytosol as well… 
2003
2003
Cloning and characterization of estrogen receptor alpha in mummichog, Fundulus heteroclitus.
Developmental exposure to 17 beta-estradiol (E(2)) induced the death of embryos and fry, malformations, sex reversal, and… 
2002
2002
CYS127S (FH-Kairouan) and D245N (FH-Tozeur) mutations in the LDL receptor gene in Tunisian families with familial hypercholesterolaemia
Familial hypercholesterolaemia (FH, MIM 143890) is a dominantly inherited metabolic disorder caused by various mutations of the… 
1992
1992
Instability of the minisatellite sequence in the first intron of the rat renin gene and localization of the gene to chromosome 13q13 between FH and PEPC loci.
A minisatellite sequence in the first intron of the rat renin gene showed five-allelic polymorphism in 11 inbred rat strains. A… 
1984
1984
Ab initio study of FH–PH3 and ClH–PH3 including the effects of electron correlation
Ab initio calculations are carried out for FH–PH3 and ClH–PH3 using a basis set including two sets of polarization functions… 
1979
1979
Further characterization of the human fumarase variant, FH2–1
1. Further investigation of fumarase using lymphoblastoid cells derived from an individual of the FH 2--1 phenotype has confirmed… 
1973
1973
Isolation and characterization of mutants of bacteriophage T4 resistant to folate analogs.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)