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Forkhead Box Protein C2

Known as: MFH-1 Protein, Mesenchyme Fork Head Protein 1, Transcription Factor FKH-14 
Forkhead box protein C2 (501aa, ~53 kDa) is encoded by the human FOXC2 gene. This protein is involved in the formation of special mesenchymal tissues… 
National Institutes of Health

Related topics

Related topics

9 relations
DNA-Binding ProteinsFOXC2 geneForkhead BoxGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Emerging roles and mechanisms of FOXC2 in cancer.
Review
2018
Review
2018
A Review on Some Natural Biopolymers and Their Applications in Angiogenesis and Tissue Engineering
One of the concerning challenges for engineering and regenerating tissues is providing a suitable condition for development of a… 
2018
2018
A Forkhead Box Protein C2 Inhibitor: Targeting Epithelial–Mesenchymal Transition and Cancer Metastasis
The epithelial–mesenchymal transition (EMT) has been suggested as a new target for therapeutic intervention of metastatic cancer… 
2018
2018
High expression of forkhead box protein C2 is associated with aggressive phenotypes and poor prognosis in clinical hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the major causes of tumor death; thus, the identification of markers related to its… 
2016
2016
Forkhead Box Protein C2 (FOXC2) Promotes the Resistance of Human Ovarian Cancer Cells to Cisplatin In Vitro and In Vivo
Background/Aims: FOXC2 has been reported to play a role in tumor progression, but the correlations of FOXC2 with the cisplatin… 
2016
2016
Forkhead Box Protein C2 Promotes Epithelial-Mesenchymal Transition, Migration and Invasion in Cisplatin-Resistant Human Ovarian Cancer Cell Line (SKOV3/CDDP)
Background/Aims: Forkhead Box Protein C2 (FOXC2) has been reported to be overexpressed in a variety of human cancers. However, it… 
Highly Cited
2015
Highly Cited
2015
Inorganic phosphate induces cancer cell mediated angiogenesis dependent on forkhead box protein C2 (FOXC2) regulated osteopontin expression
Recent studies in both rodents and humans suggest that elevated serum phosphorus, in the context of normal renal function… 
Highly Cited
2015
Highly Cited
2015
Overexpression of forkhead Box C2 promotes tumor metastasis and indicates poor prognosis in colon cancer via regulating epithelial-mesenchymal transition.
Forkhead box protein C2 (FOXC2) plays a vital role in carcinogenesis; however, its significance and prognostic value in colon… 
2013
2013
The critical role of ECM proteins within the human MSC niche in endothelial differentiation.
2013
2013
Forkhead box protein C2 contributes to invasion and metastasis of extrahepatic cholangiocarcinoma, resulting in a poor prognosis
Extrahepatic cholangiocarcinoma (EHCC) is a cancer with a poor prognosis, and the postoperative survival of patients depends on… 
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