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FOXC2 gene

Known as: Forkhead Box C2 Gene, MFH-1, FORKHEAD, DROSOPHILA, HOMOLOG-LIKE 14 
This gene plays a role in transcription and adipocyte metabolism.
National Institutes of Health

Related topics

Related topics

9 relations
FOXB1 geneForkhead Box Protein C2Hereditary lymphedema and yellow nailsHistogenic Process

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FOXC2 wt Allele

Papers overview

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Highly Cited
2017
Highly Cited
2017
Antisense lncRNA FOXC2-AS1 promotes doxorubicin resistance in osteosarcoma by increasing the expression of FOXC2.
Highly Cited
2007
Highly Cited
2007
Mutations in FOXC2 Are Strongly Associated With Primary Valve Failure in Veins of the Lower Limb
Background— Mutations in the FOXC2 gene cause lymphedema distichiasis, an inherited primary lymphedema in which a significant… 
Highly Cited
2006
Highly Cited
2006
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development.
Highly Cited
2003
Highly Cited
2003
FOXC2 haploinsufficient mice are a model for human autosomal dominant lymphedema-distichiasis syndrome.
Lymphedema-distichiasis (LD) (OMIM 153400) is a rare autosomal-dominant condition characterized by pubertal onset of lower limb… 
Highly Cited
2003
Highly Cited
2003
Reduced expression of FOXC2 and brown adipogenic genes in human subjects with insulin resistance.
OBJECTIVE We investigated subcutaneous adipose tissue expression of FOXC2 and selected genes involved in brown adipogenesis in… 
Highly Cited
2001
Highly Cited
2001
Truncating mutations in FOXC2 cause multiple lymphedema syndromes.
Hereditary lymphedemas are developmental disorders of the lymphatics resulting in edema of the extremities due to altered… 
Highly Cited
1999
Highly Cited
1999
Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles.
The murine Mf1 and Mfh1 genes have overlapping patterns of expression in the embryo and encode forkhead/winged helix… 
Highly Cited
1997
Highly Cited
1997
Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis.
Mesenchyme Fork Head-1 (MFH-1) is a forkhead (also called winged helix) transcription factor defined by a common 100-amino acid… 
Highly Cited
1997
Highly Cited
1997
The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo.
The gene mfh1, encoding a winged helix/forkhead domain transcription factor, is expressed in a dynamic pattern in paraxial and… 
Highly Cited
1996
Highly Cited
1996
Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development.
The 'winged helix' or 'forkhead' transcription factor gene family is defined by a common 100 amino acid DNA binding domain which… 
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