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FOXC2 gene

Known as: Forkhead Box C2 Gene, MFH-1, FORKHEAD, DROSOPHILA, HOMOLOG-LIKE 14 
This gene plays a role in transcription and adipocyte metabolism.
National Institutes of Health

Related topics

Related topics

9 relations
FOXB1 geneForkhead Box Protein C2Hereditary lymphedema and yellow nailsHistogenic Process

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FOXC2 wt Allele

Papers overview

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2016
2016
Forkhead Box Protein C2 (FOXC2) Promotes the Resistance of Human Ovarian Cancer Cells to Cisplatin In Vitro and In Vivo
Background/Aims: FOXC2 has been reported to play a role in tumor progression, but the correlations of FOXC2 with the cisplatin… 
2016
2016
FOXC2 augments tumor propagation and metastasis in osteosarcoma
Osteosarcoma is a highly malignant tumor that contains a small subpopulation of tumor-propagating cells (also known as tumor… 
2015
2015
Foxc2 enhances proliferation and inhibits apoptosis through activating Akt/mTORC1 signaling pathway in mouse preadipocytes
Forkhead box C2 (Foxc2) protein is a transcription factor in regulation of development, metabolism, and immunology. However, the… 
2012
2012
Nuclear localization of GLI1 and elevated expression of FOXC2 in breast cancer is associated with the basal-like phenotype.
Aberrant sonic hedgehog (SHH)/glioma-associated oncogene (GLI) signaling has been shown in the development of many tumors. The… 
Review
2009
Review
2009
The cooperative roles of Foxc1 and Foxc2 in cardiovascular development.
Fox1 and Foxc2 are closely related members of the Forkhead/Fox transcription factor family. The two Foxc genes have overlapping… 
2006
2006
Foxc2 Is a Common Mediator of Insulin and Transforming Growth Factor &bgr; Signaling to Regulate Plasminogen Activator Inhibitor Type I Gene Expression
Elevated plasma levels of plasminogen activator inhibitor type I (PAI-1), a significant risk factor of ischemic heart disease… 
2003
2003
Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians.
FOXC2 is a winged helix gene that has been shown to counteract obesity, hypertriglyceridemia, and diet-induced insulin resistance… 
2002
2002
Mechanisms of FOXC2- and FOXD1-mediated Regulation of the RIα Subunit of cAMP-dependent Protein Kinase Include Release of Transcriptional Repression and Activation by Protein Kinase Bα and cAMP*
We have reported recently that mice overexpressing the forkhead/winged helix transcription factorFOXC2 are lean and show… 
2000
2000
MFH‐1 is required for bone morphogenetic protein‐2‐induced osteoblastic differentiation of C2C12 myoblasts
1997
1997
Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures.
The very recently found evolutionarily conserved DNA-binding domain of 100 amino acids, termed the fork head domain, emerged from… 
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