Folic acid analogs, antimetabolites

Known as: Folic Acid Analogue, Folic Acid Derivative, Folic acid analogues 
A substance derived from folic acid that acts as a precursor or cofactor of enzymes and inhibitors involved in biosynthesis of amino acids, proteins… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
02419472017

Papers overview

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2014
2014
Codelivery of multiple drugs with one kind of drug carriers provided a promising strategy to suppress the drug resistance and… (More)
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2008
2008
The folate receptor (FR) is highly expressed on most epithelial cancer cells, while normal cells show only restricted expression… (More)
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2006
2006
UNLABELLED Folic acid was linked regioselectively through its alpha- and gamma-carboxyl groups to 4-fluorobenzylamine (FBA), and… (More)
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2004
2004
Thymidylate synthase (EC 2.1.1.45) (TS) catalyzes the conversion of dUMP to dTMP and is therefore indispensable for DNA… (More)
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1996
1996
UNLABELLED Folate binding protein (FBP) GP38 is a membrane-associated glycoprotein that mediates the intracellular transport of… (More)
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1985
1985
Immunosuppressive drugs have been used during the last 30 years in treatment of patients with severe rheumatoid arthritis. The… (More)
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1985
1985
The activity of a series of folic acid analogues as substrates for partially purified mouse liver folylpolyglutamate synthetase… (More)
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Highly Cited
1968
Highly Cited
1968
Transport of methotrexate (4amino-lo-methylpteroylglutamic acid), a structural analogue of folic acid, was studied in L1210 mouse… (More)
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