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Folic acid analogs, antimetabolites

Known as: Folic Acid Analogue, Folic Acid Derivative, Folic acid analogues 
A substance derived from folic acid that acts as a precursor or cofactor of enzymes and inhibitors involved in biosynthesis of amino acids, proteins… 
National Institutes of Health

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Folic Acid Antagonists

Papers overview

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1983
1983
Effect of a synthetic folic acid analogue, 9-methyl-pteroylglutamic acid, on fetal chondrogenesis: ultrastructural observations.
Maternally administered folic acid antagonists (x-methyl-PGA and 9-methyl-PGA) are known to produce various skeletal… 
1973
1973
Induction of cytoplasmic respiratory deficient mutants on yeast by the folic acid analogue, methotrexate. II. Genetic analysis of the methotrexate-induced petites.
Highly Cited
1969
Highly Cited
1969
Transport energetics of the folic acid analogue, methotrexate, in L1210 leukemia cells. Enhanced accumulation by metabolic inhibitors.
Abstract Energy-dependent transport of the folic acid analogue, methotrexate, was studied in L1210 murine leukemia cells. A… 
1965
1965
Modification of Radiation Damage of Bacteria by Folic Acid Antagonists
Pittillo, Robert F. (Southern Research Institute, Birmingham, Ala.), Mary Lucas, Robert T. Blackwell, and Carolyn Woolley… 
1962
1962
Effects of folic acid on the phenylalanine tolerance test in phenylketonuria.
Phenylalanine tolerance tests were performed on four untreated children with phenylketonuria, aged 8 to 12 years, before and… 
1959
1959
The effect of combined irradiation and chemotherapy on cancer growth with special reference to studies with folic acid analogues.
During the past four years we have been investigating the effects of chemicals on the radiation sensitivity of various biological… 
1959
1959
A study of the interactions of folic acid analogues and 6-(substituted)purines as growth inhibitors.
1957
1957
Inhibition of nonfolic-acid-requiring organisms by folic acid antagonists: mechanism of reversal.
Although folic acid antagonists have been reported to be unable to inhibit nonfolic-acid-requiring organisms, it was found that… 
1950
1950
The effect of some folic acid analogues on mitosis.
1948
1948
The effect of folic acid analogues on the action of dopa decarboxylase.
The inhibitory effect of a series of folic acid displacing agents on dopa decarboxylase is reported. An attempt is made to…